Assay Report Card

Basic Information

ID: ALA3637317

Type: Binding

Description: Inhibition of ACAT in human MDM cells assessed as inhibition of foam cell formation by measuring acetylated LDL-induced [3H]cholesterol ester accumulation at 5 uM after 24 hrs in presence of 0.1 mM [3H]oleate

Organism: Homo sapiens

Cell type: MDM

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
938.227.947.94
1019.13
1017.11
1098.03
472.133.353.35
1035.13
1019.13
940.237.517.51