Antagonist activity at rat CaSR expressed in HEK293 cells assessed as inhibition of Ca2+-induced inositol monophosphate accumulation after 1 hr by FRE...

Basic Information

ID: ALA3637423

Type: Functional

Description: Antagonist activity at rat CaSR expressed in HEK293 cells assessed as inhibition of Ca2+-induced inositol monophosphate accumulation after 1 hr by FRET assay

Format: BAO_0000219

Organism: Rattus norvegicus

Cell type: HEK293

Target: Calcium sensing receptor(ALA2516)

Document: ALA3632567

Antagonist activity at rat CaSR expressed in HEK293 cells assessed as inhibition of Ca2+-induced inositol monophosphate accumulation after 1 hr by FRET assay: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA3637423

IC50

Total(8)

Parent Molecular Weight	ALogP	Polar Surface Area
391.47	2.81	2.81
421.50	2.82	2.82
431.54	3.59	3.59
377.49	3.28	3.28

Parent Molecular Weight

ALogP

Polar Surface Area

391.47

2.81

421.50

2.82

431.54

3.59

377.49

3.28

Antagonist activity at rat CaSR expressed in HEK293 cells assessed as inhibition of Ca2+-induced inositol monophosphate accumulation after 1 hr by FRE...

Basic Information

Activity Charts

Compound Summary