Antagonist activity at rat mGluR5 expressed in CHO cells assessed as inhibition of L-glutamate-induced inositol monophosphate accumulation after 1 hr ...

Basic Information

ID: ALA3637425

Type: Functional

Description: Antagonist activity at rat mGluR5 expressed in CHO cells assessed as inhibition of L-glutamate-induced inositol monophosphate accumulation after 1 hr by FRET assay

Format: BAO_0000219

Organism: Rattus norvegicus

Cell type: CHO

Target: Metabotropic glutamate receptor 5(ALA2564)

Document: ALA3632567

Antagonist activity at rat mGluR5 expressed in CHO cells assessed as inhibition of L-glutamate-induced inositol monophosphate accumulation after 1 hr by FRET assay: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA3637425

IC50

Total(8)

Parent Molecular Weight	ALogP	Polar Surface Area
391.47	2.81	2.81
421.50	2.82	2.82
431.54	3.59	3.59
377.49	3.28	3.28

Parent Molecular Weight

ALogP

Polar Surface Area

391.47

2.81

421.50

2.82

431.54

3.59

377.49

3.28

Antagonist activity at rat mGluR5 expressed in CHO cells assessed as inhibition of L-glutamate-induced inositol monophosphate accumulation after 1 hr ...

Basic Information

Activity Charts

Compound Summary