Basic Information
ID: ALA3705102
Type: Binding
Description: Binding Assay: The secondary assay was a time resolved-FRET LanthaScreen Kinase Binding Assay. (Invitrogen Corporation, Carlsbad, Calif.). This assay evaluates the ability of the test compound to compete with a fluorescently-labeled tracer molecule to bind in the ATP pocket of a kinase.
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3705102
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 402.46 | 3.29 | 3.29 |
| 480.52 | 4.71 | 4.71 |
| 395.41 | 4.87 | 4.87 |
| 317.35 | 3.45 | 3.45 |
| 353.33 | 3.70 | 3.70 |
| 452.47 | 3.53 | 3.53 |
| 438.44 | 3.54 | 3.54 |
| 332.37 | 3.39 | 3.39 |
| 371.38 | 4.50 | 4.50 |
| 388.45 | 4.18 | 4.18 |
| 378.36 | 5.79 | 5.79 |
| 377.45 | 5.93 | 5.93 |
| 404.38 | 5.03 | 5.03 |
| 388.48 | 3.78 | 3.78 |
| 360.42 | 4.17 | 4.17 |
| 437.51 | 4.36 | 4.36 |
| 438.44 | 3.54 | 3.54 |
| 438.44 | 3.54 | 3.54 |
| 452.47 | 3.93 | 3.93 |