ID: ALA3705115
Type: Binding
Description: PIM-2 Enzyme Assay: The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled peptide onto a Whatman P81 (phosphocellulose) filter plate. Assay mixtures contained 4 uM [gamma-33P] ATP (20 uCi/mL), 1.0 uM PIM2tide and 1.5 nM PIM-2 in place of PIM-1.
Format: BAO_0000357
Organism: Homo sapiens
Target: Serine/threonine-protein kinase PIM2(ALA4523)
Document: ALA3639321
BindingDB Source: 6019
Bioactivity
Activity Types for Assay ALA3705115
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
344.42 | 3.11 | 3.11 |
400.53 | 4.67 | 4.67 |
359.43 | 3.66 | 3.66 |
330.40 | 2.72 | 2.72 |
330.40 | 2.72 | 2.72 |
418.50 | 4.27 | 4.27 |
318.38 | 2.71 | 2.71 |
388.52 | 4.15 | 4.15 |
345.41 | 3.08 | 3.08 |
319.37 | 2.67 | 2.67 |
331.38 | 2.69 | 2.69 |
331.38 | 2.69 | 2.69 |
403.44 | 2.62 | 2.62 |
359.43 | 3.32 | 3.32 |
373.46 | 3.86 | 3.86 |
359.43 | 3.32 | 3.32 |
359.43 | 3.59 | 3.59 |
347.42 | 3.31 | 3.31 |
377.45 | 2.80 | 2.80 |
347.42 | 3.44 | 3.44 |
375.48 | 3.91 | 3.91 |
346.39 | 3.10 | 3.10 |
332.41 | 4.37 | 4.37 |
348.41 | 3.34 | 3.34 |
363.40 | 3.02 | 3.02 |
363.40 | 3.02 | 3.02 |
375.48 | 3.96 | 3.96 |
361.45 | 3.57 | 3.57 |
371.44 | 3.61 | 3.61 |
375.48 | 4.09 | 4.09 |
375.48 | 4.09 | 4.09 |
361.45 | 3.70 | 3.70 |
361.45 | 3.70 | 3.70 |
389.50 | 4.48 | 4.48 |
389.50 | 4.48 | 4.48 |
365.41 | 3.45 | 3.45 |
388.43 | 2.87 | 2.87 |
355.35 | 2.92 | 2.92 |
365.41 | 3.45 | 3.45 |
353.39 | 3.92 | 3.92 |
353.39 | 3.92 | 3.92 |
377.42 | 3.41 | 3.41 |
377.42 | 3.41 | 3.41 |
359.43 | 3.47 | 3.47 |
416.49 | 2.53 | 2.53 |
432.48 | 2.46 | 2.46 |
375.43 | 2.44 | 2.44 |
389.46 | 3.09 | 3.09 |
426.32 | 4.07 | 4.07 |
381.39 | 3.16 | 3.16 |
381.39 | 3.16 | 3.16 |
345.41 | 3.08 | 3.08 |
336.35 | 1.68 | 1.68 |
426.32 | 4.07 | 4.07 |
387.49 | 4.19 | 4.19 |
423.52 | 4.98 | 4.98 |
373.46 | 3.71 | 3.71 |
387.49 | 4.10 | 4.10 |
413.53 | 4.49 | 4.49 |
401.51 | 4.35 | 4.35 |
465.56 | 4.35 | 4.35 |
375.43 | 2.44 | 2.44 |
389.46 | 3.09 | 3.09 |
339.36 | 4.13 | 4.13 |
354.37 | 3.71 | 3.71 |
355.36 | 3.11 | 3.11 |
456.32 | 4.18 | 4.18 |
442.29 | 3.79 | 3.79 |
417.49 | 4.29 | 4.29 |
403.46 | 3.90 | 3.90 |
453.52 | 5.08 | 5.08 |
439.49 | 4.69 | 4.69 |
434.48 | 2.61 | 2.61 |
391.45 | 3.76 | 3.76 |
421.48 | 3.12 | 3.12 |
417.51 | 3.42 | 3.42 |
381.39 | 3.16 | 3.16 |
395.41 | 3.55 | 3.55 |
391.45 | 3.72 | 3.72 |
399.38 | 3.46 | 3.46 |
363.40 | 3.02 | 3.02 |
417.49 | 4.29 | 4.29 |
391.45 | 3.72 | 3.72 |
402.43 | 3.96 | 3.96 |
395.41 | 3.55 | 3.55 |
395.41 | 3.55 | 3.55 |
405.48 | 4.15 | 4.15 |
423.47 | 4.10 | 4.10 |
395.41 | 3.55 | 3.55 |
349.37 | 2.63 | 2.63 |
367.36 | 2.77 | 2.77 |
407.45 | 3.42 | 3.42 |
425.44 | 3.56 | 3.56 |
451.50 | 3.44 | 3.44 |
396.42 | 2.84 | 2.84 |
378.43 | 2.70 | 2.70 |
421.48 | 3.62 | 3.62 |
465.53 | 3.33 | 3.33 |
389.46 | 2.83 | 2.83 |
377.42 | 3.42 | 3.42 |