Basic Information
ID: ALA3705150
Type: Binding
Description: Binding Assay: 5-HT1D binding assays (agonist radioligand)were performed using bovine caudate membranes according to the methods of Heuring and Peroutka (J. Neurosci 1987, 7: 894-903). 5-HT1B (rat cerebral cortex) binding assays (agonist radioligand) were performed according to the method of Hoyer et. al. (Eur. J. Pharmacol. 1995, 118: 1-12).
Organism: Bos taurus
Tissue: Cerebral cortex
Activity Charts
Bioactivity
Activity Types for Assay ALA3705150
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 295.41 | 1.32 | 1.32 |
| 322.41 | 3.61 | 3.61 |
| 390.51 | 4.01 | 4.01 |
| 350.49 | 3.85 | 3.85 |
| 336.46 | 3.99 | 3.99 |
| 320.40 | 3.52 | 3.52 |
| 338.48 | 4.08 | 4.08 |
| 314.46 | 3.59 | 3.59 |
| 312.44 | 3.37 | 3.37 |
| 326.47 | 3.76 | 3.76 |
| 326.47 | 3.24 | 3.24 |
| 352.51 | 4.47 | 4.47 |
| 338.48 | 3.90 | 3.90 |
| 338.48 | 3.90 | 3.90 |
| 324.45 | 3.69 | 3.69 |
| 308.38 | 3.22 | 3.22 |