Assay Report Card

Basic Information

ID: ALA3705334

Type: Binding

Description: Inhibition Assay: The inhibitory activity of the compound against human dUTPase was determined by measuring the production of [5-3H]deoxyuridine monophosphate from [5-3H]deoxyuridine triphosphate.

Organism: Homo sapiens

Activity Charts

Bioactivity

Activity Types for Assay ALA3705334

IC50

Total(143)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
428.49	3.52	3.52
381.45	1.05	1.05
411.48	1.06	1.06
415.90	1.70	1.70
415.90	1.70	1.70
415.90	1.70	1.70
451.55	1.84	1.84
451.55	1.54	1.54
437.52	1.37	1.37
437.52	1.37	1.37
455.51	1.51	1.51
399.47	1.80	1.80
429.50	1.81	1.81
469.56	2.59	2.59
433.53	1.95	1.95
447.56	2.48	2.48
455.53	0.73	0.73
423.49	0.95	0.95
451.55	1.90	1.90
441.48	0.95	0.95
483.56	2.15	2.15
499.59	2.40	2.40
439.56	1.52	1.52
423.49	1.12	1.12
479.60	2.32	2.32
545.51	2.85	2.85
501.61	2.64	2.64
569.68	3.19	3.19
515.63	3.03	3.03
535.57	2.68	2.68
497.59	2.46	2.46
437.52	1.34	1.34
469.54	1.90	1.90
469.54	2.04	2.04
483.56	2.15	2.15
451.55	1.76	1.76
469.54	1.68	1.68
513.62	2.79	2.79
463.56	1.76	1.76
465.57	2.01	2.01
451.55	1.90	1.90
409.46	0.56	0.56
469.54	1.90	1.90
483.56	2.15	2.15
455.51	1.51	1.51
535.57	2.68	2.68
523.61	2.60	2.60
477.58	2.08	2.08
481.55	1.90	1.90
465.57	2.29	2.29
477.58	2.29	2.29
437.52	1.51	1.51
455.51	1.48	1.48
451.55	1.73	1.73
453.52	0.58	0.58
467.54	1.14	1.14
485.53	1.28	1.28
447.46	0.71	0.71
483.44	1.82	1.82
453.56	2.01	2.01
465.45	1.52	1.52
483.44	1.66	1.66
501.43	2.12	2.12
461.49	1.27	1.27
421.48	0.59	0.59
439.53	1.62	1.62
453.56	2.01	2.01
451.55	1.76	1.76
447.46	1.23	1.23
435.50	0.98	0.98
435.50	0.98	0.98
429.47	0.93	0.93
465.57	2.15	2.15
439.53	1.76	1.76
439.53	1.76	1.76
465.45	1.36	1.36
423.49	1.15	1.15
453.56	2.15	2.15
453.56	2.15	2.15
515.46	2.16	2.16
451.55	1.76	1.76
429.50	1.61	1.61
443.52	1.92	1.92
465.48	1.89	1.89
483.59	2.53	2.53
515.63	2.17	2.17
407.49	1.29	1.29
381.45	0.97	0.97
385.42	0.72	0.72
447.49	1.75	1.75
447.52	2.65	2.65
451.52	2.09	2.09
453.54	2.32	2.32
449.57	2.57	2.57
421.52	1.62	1.62
421.52	1.93	1.93
449.57	2.71	2.71
417.43	1.25	1.25
407.49	1.40	1.40
435.55	2.18	2.18
399.47	1.64	1.64
469.56	2.42	2.42
419.50	1.39	1.39
487.55	2.56	2.56
439.51	1.93	1.93
505.54	2.70	2.70
351.43	1.00	1.00
448.55	1.07	1.07
450.34	2.35	2.35
456.37	2.42	2.42
450.34	2.35	2.35
460.35	1.81	1.81
447.46	1.65	1.65
501.56	2.27	2.27
474.58	2.27	2.27
545.28	2.63	2.63
399.44	1.19	1.19
395.48	1.36	1.36
395.48	1.36	1.36
460.35	1.81	1.81
461.49	1.69	1.69
465.57	2.37	2.37
421.52	2.08	2.08
379.44	0.80	0.80
409.46	0.81	0.81
423.49	1.06	1.06
449.53	1.59	1.59
470.55	1.98	1.98
474.50	0.91	0.91
423.49	0.81	0.81
453.52	0.75	0.75
487.55	2.94	2.94
425.48	1.54	1.54
469.56	1.66	1.66
505.54	1.94	1.94
505.54	1.94	1.94
377.47	0.92	0.92
421.52	1.22	1.22
451.55	1.49	1.49
513.59	1.58	1.58
441.55	2.25	2.25