Basic Information
ID: ALA3705472
Type: Binding
Description: Inhibition Assay: Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known (see., e.g., National Committee for Clinical Laboratory Standards 2000 Performance standards for antimicrobial disk susceptibility tests: approved standard, 7th ed. M2-A7, vol. 20, no. 1, Committee for Clinical Laboratory Standards, Wayne, Pa.).
Format: BAO_0000357
Organism: Homo sapiens
Target: Dihydrofolate reductase(ALA202)
Document: ALA3638993
BindingDB Source: 6486
Activity Charts
Bioactivity
Activity Types for Assay ALA3705472
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 251.29 | 2.04 | 2.04 |
| 265.32 | 2.35 | 2.35 |
| 266.30 | 2.47 | 2.47 |
| 278.31 | 2.66 | 2.66 |
| 292.34 | 2.97 | 2.97 |
| 449.54 | 3.90 | 3.90 |
| 344.42 | 4.32 | 4.32 |
| 393.49 | 3.65 | 3.65 |
| 381.44 | 3.81 | 3.81 |
| 344.42 | 3.63 | 3.63 |
| 389.46 | 2.59 | 2.59 |
| 401.50 | 4.18 | 4.18 |
| 421.92 | 4.53 | 4.53 |
| 387.47 | 3.87 | 3.87 |
| 370.42 | 4.01 | 4.01 |
| 386.48 | 4.48 | 4.48 |
| 386.48 | 4.48 | 4.48 |
| 251.29 | 2.04 | 2.04 |
| 296.33 | 2.48 | 2.48 |
| 310.36 | 2.27 | 2.27 |
| 289.34 | 3.25 | 3.25 |
| 376.42 | 1.69 | 1.69 |
| 275.32 | 3.32 | 3.32 |
| 290.33 | 2.90 | 2.90 |
| 289.34 | 3.19 | 3.19 |
| 362.44 | 2.81 | 2.81 |
| 430.48 | 4.28 | 4.28 |
| 453.92 | 3.41 | 3.41 |
| 433.50 | 3.07 | 3.07 |
| 290.33 | 2.65 | 2.65 |
| 315.76 | 2.31 | 2.31 |
| 312.33 | 1.06 | 1.06 |
| 417.45 | 3.04 | 3.04 |
| 340.38 | 2.80 | 2.80 |
| 419.47 | 2.76 | 2.76 |
| 372.46 | 4.17 | 4.17 |
| 373.38 | 2.80 | 2.80 |
| 315.76 | 2.83 | 2.83 |
| 422.51 | 3.97 | 3.97 |
| 289.34 | 3.25 | 3.25 |