Basic Information
ID: ALA3705547
Type: Binding
Description: Kinase Assay: To evaluate the in-vitro kinase potency of the compounds, they were screened against CDK 2 and CDK9. Kinase assays were performed in 96-well plates using recombinant CDK/cyclins generated at Cyclacel. Ltd Dundee, UK.
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3705547
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 397.53 | 3.60 | 3.60 |
| 383.50 | 3.29 | 3.29 |
| 402.93 | 4.24 | 4.24 |
| 386.48 | 3.73 | 3.73 |
| 381.48 | 2.81 | 2.81 |
| 318.43 | 2.55 | 2.55 |
| 332.45 | 2.80 | 2.80 |
| 332.45 | 2.94 | 2.94 |
| 369.47 | 2.99 | 2.99 |
| 397.53 | 3.60 | 3.60 |
| 437.47 | 4.00 | 4.00 |
| 383.50 | 3.29 | 3.29 |
| 383.50 | 3.29 | 3.29 |
| 341.42 | 2.21 | 2.21 |
| 395.39 | 2.75 | 2.75 |
| 423.44 | 3.53 | 3.53 |