Basic Information
ID: ALA3705561
Type: Binding
Description: Inhibition Assay: Inhibition of human C1s was determined by the method described in [0092]-[0098] using native human activated C1s complement component from Calbiochem at 29 nM and Val-Ser-Arg-pNA (S2314) at 8 mM, 6 mM, and 4 mM as substrate; results are reported as Ki values (nanomolar).
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3705561
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 690.87 | 3.06 | 3.06 |
| 681.90 | 2.38 | 2.38 |
| 653.89 | 2.51 | 2.51 |
| 707.94 | 2.77 | 2.77 |
| 695.93 | 2.77 | 2.77 |
| 695.93 | 2.77 | 2.77 |
| 639.87 | 2.12 | 2.12 |
| 711.93 | 2.00 | 2.00 |
| 633.82 | 2.37 | 2.37 |
| 710.95 | 2.51 | 2.51 |
| 696.92 | 2.17 | 2.17 |
| 709.96 | 3.16 | 3.16 |
| 697.90 | 2.60 | 2.60 |
| 663.85 | 2.00 | 2.00 |
| 709.96 | 3.01 | 3.01 |
| 646.86 | 3.36 | 3.36 |
| 649.82 | 1.61 | 1.61 |
| 711.93 | 2.99 | 2.99 |
| 704.89 | 3.15 | 3.15 |
| 647.85 | 2.76 | 2.76 |
| 638.80 | 0.81 | 0.81 |