Basic Information
ID: ALA3705563
Type: Binding
Description: Inhibition Assay: Inhibition of human C1r was determined by the method described in [0092]-[0098] using native human activated C1r complement component from Calbiochem at 100 nM and Val-Ser-Arg-pNA (S2314) at 16 mM, 12 mM, and 8 mM as substrate; results are reported as Ki values (nanomolar).
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3705563
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 690.87 | 3.06 | 3.06 |
| 681.90 | 2.38 | 2.38 |
| 653.89 | 2.51 | 2.51 |
| 707.94 | 2.77 | 2.77 |
| 695.93 | 2.77 | 2.77 |
| 695.93 | 2.77 | 2.77 |
| 639.87 | 2.12 | 2.12 |
| 711.93 | 2.00 | 2.00 |
| 633.82 | 2.37 | 2.37 |
| 710.95 | 2.51 | 2.51 |
| 696.92 | 2.17 | 2.17 |
| 709.96 | 3.16 | 3.16 |
| 697.90 | 2.60 | 2.60 |
| 663.85 | 2.00 | 2.00 |
| 709.96 | 3.01 | 3.01 |
| 649.82 | 1.61 | 1.61 |
| 711.93 | 2.99 | 2.99 |
| 704.89 | 3.15 | 3.15 |
| 647.85 | 2.76 | 2.76 |