Basic Information
ID: ALA3705628
Type: Binding
Description: Cell Based Assay: mGluR5 activity was determined in a cell-based assay.
Format: BAO_0000219
Organism: Rattus norvegicus
Target: Metabotropic glutamate receptor 5(ALA2564)
Document: ALA3638497
BindingDB Source: 6072
Activity Charts
Bioactivity
Activity Types for Assay ALA3705628
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 291.31 | 3.52 | 3.52 |
| 325.75 | 4.17 | 4.17 |
| 359.31 | 4.54 | 4.54 |
| 327.29 | 3.80 | 3.80 |
| 295.30 | 2.25 | 2.25 |
| 309.30 | 3.66 | 3.66 |
| 306.33 | 3.22 | 3.22 |
| 310.29 | 3.06 | 3.06 |
| 305.34 | 3.83 | 3.83 |
| 312.35 | 3.29 | 3.29 |
| 360.20 | 4.83 | 4.83 |
| 360.20 | 4.83 | 4.83 |
| 298.33 | 2.98 | 2.98 |
| 312.35 | 3.29 | 3.29 |
| 326.74 | 3.57 | 3.57 |
| 326.74 | 3.57 | 3.57 |
| 292.30 | 2.92 | 2.92 |
| 320.35 | 3.48 | 3.48 |
| 310.32 | 1.96 | 1.96 |
| 306.33 | 3.22 | 3.22 |
| 296.29 | 1.65 | 1.65 |
| 322.32 | 2.92 | 2.92 |
| 293.29 | 2.31 | 2.31 |
| 313.34 | 2.68 | 2.68 |
| 330.34 | 3.43 | 3.43 |
| 366.32 | 4.00 | 4.00 |
| 292.30 | 2.92 | 2.92 |
| 312.35 | 3.29 | 3.29 |
| 323.34 | 2.85 | 2.85 |
| 313.34 | 2.68 | 2.68 |
| 366.32 | 4.00 | 4.00 |
| 299.31 | 2.37 | 2.37 |
| 311.37 | 2.95 | 2.95 |
| 325.40 | 3.26 | 3.26 |
| 326.39 | 2.66 | 2.66 |
| 324.32 | 2.43 | 2.43 |
| 324.32 | 2.43 | 2.43 |
| 269.30 | 2.55 | 2.55 |
| 283.33 | 2.94 | 2.94 |
| 297.36 | 3.33 | 3.33 |
| 311.39 | 3.72 | 3.72 |
| 299.33 | 2.18 | 2.18 |
| 306.33 | 2.29 | 2.29 |
| 320.36 | 2.60 | 2.60 |
| 340.77 | 2.94 | 2.94 |
| 313.36 | 2.30 | 2.30 |
| 293.29 | 2.31 | 2.31 |
| 307.31 | 2.62 | 2.62 |
| 311.28 | 2.45 | 2.45 |
| 311.28 | 2.45 | 2.45 |
| 329.27 | 2.59 | 2.59 |
| 327.73 | 2.96 | 2.96 |
| 327.73 | 2.96 | 2.96 |
| 312.37 | 3.12 | 3.12 |
| 300.32 | 1.57 | 1.57 |
| 331.33 | 2.84 | 2.84 |
| 311.28 | 2.45 | 2.45 |
| 325.30 | 2.76 | 2.76 |
| 311.28 | 2.45 | 2.45 |
| 331.33 | 2.82 | 2.82 |
| 321.34 | 2.87 | 2.87 |
| 327.73 | 2.96 | 2.96 |
| 308.30 | 2.01 | 2.01 |
| 323.31 | 2.32 | 2.32 |
| 307.31 | 2.62 | 2.62 |
| 367.31 | 3.39 | 3.39 |
| 369.45 | 3.98 | 3.98 |
| 349.38 | 3.53 | 3.53 |
| 349.32 | 3.31 | 3.31 |
| 342.34 | 1.47 | 1.47 |
| 392.24 | 3.44 | 3.44 |
| 372.18 | 3.07 | 3.07 |
| 343.29 | 2.92 | 2.92 |
| 361.28 | 3.39 | 3.39 |
| 323.31 | 2.32 | 2.32 |
| 361.28 | 3.33 | 3.33 |
| 325.30 | 2.76 | 2.76 |