Assay Report Card

Basic Information

ID: ALA3705794

Type: Binding

Description: Enzyme Inhibition Assay: Heterocyclic analogs of propargyl-linked inhibitors of the third generation analogs were evaluated in enzyme inhibition assays, assessed for S. aureus and S. pyogenes inhibition, and evaluated for mammalian cell toxicity.

Organism: Staphylococcus aureus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
372.474.094.09
386.504.404.40
328.423.463.46
358.453.473.47
358.453.473.47
367.451.951.95
359.433.183.18
373.463.433.43
359.432.872.87
358.453.783.78
359.432.872.87
372.474.034.03
329.412.862.86
329.412.862.86
330.402.252.25