Basic Information
ID: ALA3705899
Type: Binding
Description: In Vitro Assay: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compound at various concentrations for 1 hour at room temperature in 0.1 M Hepes buffer, pH 7.5, containing 1 mM MgCl2, 1 M NaCl and 0.05% CHAPS. A synthetic substrate Z-Lys-thiobenzyl and 2,4-dinitrobenzenesulfonyl-fluoresceine are added to final concentrations of 200 μM and 25 μM, respectively. The increase in fluorescence is recorded at excitation of 485 nm and emission at 535 nm in a microplate spectrofluorimeter. IC50 values are calculated from percentage of inhibition of complement factor D-activity as a function of test compound concentration.
Activity Charts
Bioactivity
Activity Types for Assay ALA3705899
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 563.95 | 3.47 | 3.47 |
| 524.94 | 3.57 | 3.57 |
| 584.05 | 4.56 | 4.56 |
| 450.50 | 1.35 | 1.35 |
| 475.88 | 3.62 | 3.62 |
| 423.45 | 2.83 | 2.83 |
| 424.44 | 2.22 | 2.22 |
| 577.03 | 3.70 | 3.70 |
| 505.91 | 3.15 | 3.15 |
| 424.44 | 2.22 | 2.22 |
| 574.03 | 3.37 | 3.37 |
| 457.89 | 3.48 | 3.48 |
| 439.45 | 2.53 | 2.53 |
| 588.06 | 3.37 | 3.37 |
| 463.92 | 3.54 | 3.54 |
| 561.03 | 4.46 | 4.46 |
| 453.47 | 2.36 | 2.36 |
| 459.43 | 3.11 | 3.11 |
| 503.58 | 3.39 | 3.39 |
| 589.04 | 4.24 | 4.24 |
| 590.08 | 3.61 | 3.61 |
| 575.02 | 3.45 | 3.45 |
| 560.99 | 3.46 | 3.46 |
| 603.07 | 4.23 | 4.23 |
| 563.01 | 3.70 | 3.70 |
| 576.05 | 3.27 | 3.27 |
| 467.46 | 2.53 | 2.53 |
| 467.46 | 2.53 | 2.53 |
| 447.47 | 2.13 | 2.13 |
| 406.45 | 2.14 | 2.14 |
| 420.47 | 1.82 | 1.82 |
| 454.92 | 2.47 | 2.47 |
| 434.50 | 2.13 | 2.13 |
| 488.47 | 2.84 | 2.84 |
| 438.46 | 1.96 | 1.96 |
| 445.48 | 1.69 | 1.69 |
| 499.37 | 2.58 | 2.58 |
| 436.47 | 1.52 | 1.52 |
| 450.50 | 1.83 | 1.83 |
| 504.47 | 2.72 | 2.72 |
| 512.57 | 3.61 | 3.61 |
| 496.57 | 3.49 | 3.49 |
| 485.55 | 2.61 | 2.61 |
| 537.05 | 4.20 | 4.20 |
| 543.07 | 4.26 | 4.26 |
| 434.50 | 2.13 | 2.13 |
| 454.92 | 2.47 | 2.47 |
| 488.47 | 2.84 | 2.84 |
| 504.47 | 2.72 | 2.72 |
| 436.47 | 1.52 | 1.52 |
| 436.47 | 1.52 | 1.52 |
| 438.46 | 1.96 | 1.96 |
| 454.92 | 2.47 | 2.47 |
| 496.57 | 3.49 | 3.49 |
| 456.45 | 2.10 | 2.10 |
| 484.94 | 2.48 | 2.48 |
| 484.94 | 2.48 | 2.48 |
| 472.91 | 2.61 | 2.61 |
| 472.91 | 2.61 | 2.61 |
| 468.95 | 2.78 | 2.78 |
| 468.95 | 2.78 | 2.78 |
| 468.95 | 2.78 | 2.78 |
| 489.36 | 3.12 | 3.12 |
| 489.36 | 3.12 | 3.12 |
| 490.90 | 2.75 | 2.75 |
| 470.53 | 2.97 | 2.97 |
| 470.53 | 2.97 | 2.97 |
| 441.52 | 1.58 | 1.58 |
| 460.95 | 2.53 | 2.53 |
| 435.49 | 1.52 | 1.52 |
| 468.95 | 3.03 | 3.03 |
| 468.95 | 3.03 | 3.03 |
| 519.39 | 2.66 | 2.66 |
| 498.97 | 2.39 | 2.39 |
| 446.51 | 2.31 | 2.31 |
| 496.57 | 3.41 | 3.41 |
| 426.52 | 2.20 | 2.20 |
| 442.52 | 1.17 | 1.17 |
| 442.52 | 1.17 | 1.17 |
| 412.49 | 1.95 | 1.95 |
| 490.57 | 1.68 | 1.68 |
| 480.96 | 2.96 | 2.96 |
| 496.96 | 2.80 | 2.80 |
| 434.50 | 1.86 | 1.86 |
| 446.51 | 2.17 | 2.17 |
| 448.53 | 2.42 | 2.42 |
| 448.53 | 2.42 | 2.42 |
| 468.95 | 2.51 | 2.51 |
| 468.95 | 2.51 | 2.51 |
| 452.49 | 2.00 | 2.00 |
| 452.49 | 2.00 | 2.00 |
| 486.94 | 2.65 | 2.65 |
| 464.53 | 2.09 | 2.09 |
| 458.52 | 1.21 | 1.21 |
| 444.49 | 0.96 | 0.96 |
| 444.49 | 0.82 | 0.82 |
| 458.52 | 1.21 | 1.21 |
| 488.55 | 0.97 | 0.97 |
| 492.54 | 1.40 | 1.40 |
| 478.51 | 1.53 | 1.53 |
| 443.51 | 0.52 | 0.52 |
| 448.53 | 2.38 | 2.38 |
| 430.51 | 1.02 | 1.02 |
| 448.53 | 3.26 | 3.26 |
| 482.54 | 3.81 | 3.81 |
| 477.49 | 2.63 | 2.63 |
| 459.50 | 2.49 | 2.49 |
| 477.49 | 2.63 | 2.63 |
| 493.95 | 3.14 | 3.14 |
| 538.40 | 3.25 | 3.25 |
| 543.50 | 3.39 | 3.39 |
| 511.94 | 3.28 | 3.28 |
| 499.98 | 3.21 | 3.21 |
| 475.96 | 3.20 | 3.20 |
| 437.48 | 2.87 | 2.87 |
| 439.45 | 3.30 | 3.30 |
| 485.90 | 4.14 | 4.14 |
| 461.90 | 4.09 | 4.09 |
| 461.44 | 4.58 | 4.58 |
| 488.92 | 3.35 | 3.35 |
| 507.44 | 2.51 | 2.51 |
| 475.43 | 3.57 | 3.57 |
| 500.44 | 3.85 | 3.85 |
| 471.92 | 3.92 | 3.92 |
| 505.45 | 3.73 | 3.73 |
| 498.94 | 3.94 | 3.94 |
| 483.93 | 3.93 | 3.93 |
| 491.43 | 3.07 | 3.07 |
| 563.99 | 4.04 | 4.04 |
| 557.97 | 3.22 | 3.22 |
| 487.44 | 4.10 | 4.10 |
| 469.90 | 3.53 | 3.53 |
| 489.45 | 4.35 | 4.35 |
| 520.33 | 3.73 | 3.73 |
| 546.51 | 3.61 | 3.61 |
| 475.43 | 4.10 | 4.10 |
| 487.44 | 3.96 | 3.96 |
| 511.46 | 4.15 | 4.15 |
| 501.90 | 3.59 | 3.59 |
| 519.89 | 3.32 | 3.32 |
| 473.41 | 3.88 | 3.88 |
| 471.88 | 2.66 | 2.66 |
| 525.89 | 4.46 | 4.46 |
| 482.34 | 3.96 | 3.96 |
| 469.90 | 3.67 | 3.67 |
| 488.32 | 3.91 | 3.91 |
| 521.52 | 4.79 | 4.79 |
| 492.54 | 4.74 | 4.74 |
| 546.35 | 3.70 | 3.70 |
| 590.03 | 2.91 | 2.91 |
| 457.94 | 3.59 | 3.59 |
| 546.35 | 3.70 | 3.70 |
| 489.45 | 4.35 | 4.35 |
| 432.48 | 3.16 | 3.16 |
| 532.33 | 3.61 | 3.61 |
| 454.56 | 3.96 | 3.96 |
| 493.47 | 4.01 | 4.01 |
| 543.98 | 3.70 | 3.70 |
| 438.46 | 3.11 | 3.11 |
| 487.92 | 3.03 | 3.03 |
| 503.33 | 3.62 | 3.62 |
| 469.90 | 3.67 | 3.67 |
| 451.91 | 3.39 | 3.39 |
| 503.33 | 3.62 | 3.62 |
| 459.48 | 3.07 | 3.07 |
| 457.89 | 3.67 | 3.67 |
| 483.33 | 3.36 | 3.36 |
| 422.42 | 2.74 | 2.74 |
| 435.46 | 3.02 | 3.02 |
| 457.94 | 3.44 | 3.44 |
| 505.43 | 4.24 | 4.24 |
| 455.88 | 3.99 | 3.99 |
| 455.90 | 2.51 | 2.51 |
| 475.93 | 3.58 | 3.58 |
| 530.47 | 4.78 | 4.78 |
| 465.94 | 3.92 | 3.92 |
| 505.91 | 2.98 | 2.98 |
| 471.92 | 3.92 | 3.92 |
| 451.91 | 3.53 | 3.53 |
| 513.96 | 3.69 | 3.69 |
| 422.42 | 2.74 | 2.74 |
| 487.92 | 3.30 | 3.30 |
| 489.45 | 4.49 | 4.49 |
| 518.43 | 3.99 | 3.99 |
| 518.95 | 3.16 | 3.16 |
| 475.88 | 3.62 | 3.62 |
| 493.42 | 4.05 | 4.05 |
| 489.45 | 4.49 | 4.49 |
| 444.85 | 3.20 | 3.20 |
| 489.31 | 3.31 | 3.31 |
| 453.45 | 3.16 | 3.16 |
| 503.92 | 2.01 | 2.01 |
| 471.88 | 2.66 | 2.66 |
| 546.40 | 3.66 | 3.66 |
| 471.52 | 3.60 | 3.60 |
| 515.93 | 3.07 | 3.07 |
| 456.87 | 3.27 | 3.27 |
| 503.92 | 2.01 | 2.01 |
| 499.93 | 3.21 | 3.21 |
| 505.91 | 3.25 | 3.25 |
| 489.91 | 4.01 | 4.01 |
| 532.94 | 2.74 | 2.74 |
| 499.93 | 3.06 | 3.06 |
| 475.88 | 3.62 | 3.62 |
| 575.02 | 3.32 | 3.32 |
| 469.90 | 3.53 | 3.53 |
| 532.94 | 2.74 | 2.74 |
| 499.93 | 3.06 | 3.06 |
| 473.89 | 2.64 | 2.64 |
| 442.43 | 2.36 | 2.36 |
| 499.93 | 3.68 | 3.68 |
| 526.39 | 3.18 | 3.18 |
| 489.43 | 4.36 | 4.36 |
| 449.47 | 2.99 | 2.99 |
| 471.92 | 4.06 | 4.06 |
| 546.96 | 3.13 | 3.13 |
| 509.44 | 3.99 | 3.99 |
| 513.96 | 3.60 | 3.60 |
| 493.42 | 4.05 | 4.05 |
| 489.50 | 3.08 | 3.08 |
| 418.46 | 2.27 | 2.27 |
| 489.45 | 4.35 | 4.35 |
| 452.90 | 2.93 | 2.93 |
| 533.96 | 3.93 | 3.93 |
| 442.43 | 2.36 | 2.36 |
| 513.96 | 3.72 | 3.72 |
| 510.42 | 3.38 | 3.38 |
| 470.51 | 1.85 | 1.85 |
| 469.45 | 3.80 | 3.80 |
| 489.50 | 3.08 | 3.08 |
| 513.96 | 3.86 | 3.86 |
| 458.88 | 2.88 | 2.88 |
| 420.47 | 3.16 | 3.16 |
| 519.94 | 3.54 | 3.54 |
| 532.94 | 2.98 | 2.98 |
| 507.90 | 3.96 | 3.96 |
| 436.45 | 2.41 | 2.41 |
| 575.02 | 3.32 | 3.32 |
| 533.92 | 3.41 | 3.41 |
| 513.96 | 3.72 | 3.72 |
| 501.90 | 3.11 | 3.11 |
| 438.88 | 3.25 | 3.25 |
| 532.98 | 3.72 | 3.72 |
| 491.43 | 3.07 | 3.07 |
| 589.00 | 3.09 | 3.09 |
| 433.47 | 3.21 | 3.21 |
| 547.01 | 4.47 | 4.47 |
| 505.96 | 3.12 | 3.12 |
| 437.89 | 3.85 | 3.85 |
| 589.00 | 3.09 | 3.09 |
| 500.44 | 3.85 | 3.85 |
| 455.90 | 2.51 | 2.51 |
| 417.47 | 2.88 | 2.88 |
| 461.93 | 2.57 | 2.57 |
| 486.93 | 3.63 | 3.63 |
| 503.46 | 4.04 | 4.04 |
| 489.50 | 3.08 | 3.08 |
| 464.96 | 2.90 | 2.90 |
| 493.92 | 3.72 | 3.72 |
| 487.44 | 4.27 | 4.27 |
| 493.47 | 4.01 | 4.01 |
| 525.97 | 4.24 | 4.24 |
| 489.45 | 4.41 | 4.41 |
| 527.98 | 4.12 | 4.12 |
| 474.44 | 4.84 | 4.84 |
| 540.37 | 3.75 | 3.75 |
| 551.53 | 5.84 | 5.84 |
| 511.41 | 4.19 | 4.19 |
| 575.50 | 3.65 | 3.65 |
| 546.96 | 3.32 | 3.32 |
| 532.33 | 3.61 | 3.61 |
| 451.53 | 3.23 | 3.23 |
| 531.95 | 4.19 | 4.19 |
| 526.01 | 4.51 | 4.51 |
| 489.45 | 4.36 | 4.36 |
| 462.92 | 1.96 | 1.96 |
| 445.52 | 4.32 | 4.32 |
| 554.32 | 4.86 | 4.86 |
| 513.96 | 3.47 | 3.47 |
| 503.48 | 4.66 | 4.66 |
| 541.03 | 4.04 | 4.04 |
| 543.42 | 5.12 | 5.12 |
| 509.87 | 4.76 | 4.76 |
| 505.91 | 3.63 | 3.63 |
| 463.97 | 3.51 | 3.51 |
| 487.89 | 3.81 | 3.81 |
| 458.93 | 2.99 | 2.99 |
| 525.89 | 4.59 | 4.59 |
| 505.43 | 4.24 | 4.24 |
| 541.43 | 4.20 | 4.20 |
| 461.40 | 3.71 | 3.71 |
| 499.93 | 3.68 | 3.68 |
| 493.87 | 3.92 | 3.92 |
| 485.95 | 4.45 | 4.45 |
| 549.96 | 3.65 | 3.65 |
| 456.45 | 2.67 | 2.67 |
| 492.43 | 3.24 | 3.24 |
| 555.99 | 3.78 | 3.78 |
| 487.44 | 4.10 | 4.10 |
| 541.89 | 4.22 | 4.22 |
| 440.44 | 2.55 | 2.55 |
| 444.90 | 3.16 | 3.16 |
| 525.97 | 4.24 | 4.24 |
| 487.92 | 2.89 | 2.89 |
| 581.55 | 5.68 | 5.68 |
| 527.00 | 3.77 | 3.77 |
| 555.99 | 3.78 | 3.78 |
| 505.45 | 3.73 | 3.73 |
| 466.52 | 3.84 | 3.84 |
| 577.97 | 3.56 | 3.56 |
| 525.89 | 4.59 | 4.59 |
| 481.94 | 3.07 | 3.07 |
| 489.36 | 3.27 | 3.27 |
| 602.04 | 3.01 | 3.01 |
| 428.40 | 2.69 | 2.69 |
| 434.46 | 2.30 | 2.30 |
| 469.52 | 2.61 | 2.61 |
| 499.93 | 3.81 | 3.81 |
| 428.40 | 2.69 | 2.69 |
| 532.98 | 3.55 | 3.55 |
| 576.05 | 3.62 | 3.62 |
| 459.55 | 4.50 | 4.50 |
| 473.89 | 2.64 | 2.64 |
| 511.41 | 4.35 | 4.35 |
| 578.37 | 4.23 | 4.23 |
| 487.44 | 4.10 | 4.10 |
| 531.49 | 4.67 | 4.67 |
| 489.45 | 4.49 | 4.49 |
| 489.45 | 4.49 | 4.49 |
| 503.48 | 4.88 | 4.88 |
| 487.88 | 3.50 | 3.50 |
| 526.35 | 3.66 | 3.66 |
| 532.38 | 3.57 | 3.57 |
| 556.37 | 3.67 | 3.67 |
| 550.32 | 3.75 | 3.75 |
| 550.38 | 3.14 | 3.14 |
| 606.49 | 4.37 | 4.37 |
| 543.92 | 2.80 | 2.80 |
| 600.03 | 4.03 | 4.03 |
| 457.89 | 3.48 | 3.48 |
| 457.89 | 3.48 | 3.48 |
| 471.92 | 4.06 | 4.06 |
| 485.95 | 4.45 | 4.45 |
| 487.92 | 2.89 | 2.89 |
| 533.92 | 3.21 | 3.21 |
| 519.89 | 3.12 | 3.12 |
| 532.37 | 3.00 | 3.00 |
| 505.91 | 2.98 | 2.98 |
| 499.93 | 3.03 | 3.03 |
| 507.90 | 4.16 | 4.16 |
| 505.45 | 3.46 | 3.46 |
| 438.88 | 3.13 | 3.13 |
| 456.87 | 3.27 | 3.27 |
| 456.87 | 3.27 | 3.27 |
| 487.92 | 3.21 | 3.21 |
| 487.92 | 3.21 | 3.21 |
| 490.44 | 3.81 | 3.81 |
| 499.45 | 4.71 | 4.71 |
| 540.90 | 4.96 | 4.96 |
| 491.43 | 3.81 | 3.81 |
| 491.43 | 3.81 | 3.81 |
| 485.90 | 3.38 | 3.38 |
| 451.46 | 2.72 | 2.72 |
| 543.94 | 3.14 | 3.14 |
| 543.94 | 3.14 | 3.14 |
| 527.94 | 3.30 | 3.30 |
| 527.94 | 3.30 | 3.30 |
| 529.96 | 3.04 | 3.04 |
| 535.99 | 2.95 | 2.95 |
| 547.49 | 3.47 | 3.47 |
| 529.96 | 2.90 | 2.90 |
| 549.96 | 3.38 | 3.38 |
| 513.96 | 3.21 | 3.21 |
| 513.96 | 3.21 | 3.21 |
| 558.01 | 3.82 | 3.82 |
| 557.03 | 3.61 | 3.61 |
| 583.06 | 4.15 | 4.15 |
| 580.02 | 3.95 | 3.95 |
| 565.60 | 3.74 | 3.74 |
| 509.49 | 2.48 | 2.48 |
| 485.90 | 3.38 | 3.38 |
| 491.88 | 3.33 | 3.33 |
| 557.97 | 3.22 | 3.22 |
| 529.96 | 3.04 | 3.04 |
| 490.44 | 3.04 | 3.04 |
| 502.93 | 2.24 | 2.24 |
| 596.57 | 4.62 | 4.62 |
| 454.92 | 2.34 | 2.34 |
| 496.57 | 4.33 | 4.33 |
| 514.56 | 4.47 | 4.47 |
| 504.47 | 3.43 | 3.43 |
| 504.47 | 3.29 | 3.29 |
| 504.47 | 3.29 | 3.29 |
| 486.94 | 2.86 | 2.86 |
| 514.99 | 3.46 | 3.46 |
| 502.93 | 1.97 | 1.97 |
| 504.93 | 2.95 | 2.95 |
| 504.93 | 2.95 | 2.95 |
| 532.94 | 2.74 | 2.74 |
| 522.92 | 3.09 | 3.09 |
| 503.94 | 3.68 | 3.68 |
| 563.40 | 3.43 | 3.43 |
| 522.46 | 3.38 | 3.38 |
| 490.90 | 2.56 | 2.56 |
| 488.91 | 1.58 | 1.58 |
| 472.91 | 2.61 | 2.61 |
| 471.92 | 3.34 | 3.34 |
| 540.91 | 3.71 | 3.71 |
| 472.91 | 2.61 | 2.61 |
| 454.92 | 2.47 | 2.47 |
| 496.96 | 2.65 | 2.65 |
| 513.00 | 2.75 | 2.75 |
| 518.95 | 3.21 | 3.21 |
| 486.94 | 2.87 | 2.87 |
| 530.99 | 2.89 | 2.89 |
| 500.96 | 3.21 | 3.21 |
| 517.95 | 3.27 | 3.27 |
| 488.91 | 1.58 | 1.58 |
| 490.90 | 2.56 | 2.56 |
| 458.88 | 2.79 | 2.79 |
| 458.88 | 2.79 | 2.79 |
| 440.89 | 2.65 | 2.65 |
| 551.45 | 3.64 | 3.64 |
| 505.91 | 3.03 | 3.03 |
| 531.34 | 3.01 | 3.01 |
| 576.99 | 3.00 | 3.00 |
| 424.46 | 3.31 | 3.31 |
| 458.48 | 3.86 | 3.86 |
| 510.42 | 3.73 | 3.73 |
| 498.94 | 2.60 | 2.60 |
| 472.90 | 2.18 | 2.18 |
| 531.99 | 3.09 | 3.09 |
| 468.92 | 3.21 | 3.21 |
| 532.98 | 3.47 | 3.47 |
| 474.90 | 3.16 | 3.16 |
| 498.94 | 2.74 | 2.74 |
| 474.95 | 3.12 | 3.12 |
| 504.92 | 2.52 | 2.52 |
| 498.94 | 3.22 | 3.22 |
| 528.97 | 2.58 | 2.58 |
| 512.97 | 3.23 | 3.23 |
| 546.50 | 3.01 | 3.01 |
| 456.96 | 3.13 | 3.13 |
| 512.97 | 3.13 | 3.13 |
| 526.01 | 3.31 | 3.31 |
| 548.97 | 2.92 | 2.92 |
| 492.89 | 3.30 | 3.30 |
| 482.94 | 3.52 | 3.52 |
| 535.00 | 2.49 | 2.49 |
| 498.94 | 2.60 | 2.60 |
| 512.97 | 3.40 | 3.40 |
| 528.97 | 2.44 | 2.44 |
| 489.91 | 2.10 | 2.10 |
| 472.91 | 2.61 | 2.61 |
| 439.90 | 2.19 | 2.19 |
| 503.94 | 2.49 | 2.49 |
| 521.93 | 2.63 | 2.63 |
| 556.04 | 3.15 | 3.15 |
| 526.95 | 2.84 | 2.84 |
| 512.97 | 2.74 | 2.74 |
| 474.90 | 2.79 | 2.79 |
| 504.92 | 2.80 | 2.80 |
| 469.94 | 4.33 | 4.33 |
| 571.78 | 3.69 | 3.69 |
| 526.95 | 2.63 | 2.63 |
| 519.35 | 2.90 | 2.90 |
| 488.92 | 3.68 | 3.68 |
| 468.92 | 3.34 | 3.34 |
| 456.96 | 3.26 | 3.26 |
| 533.96 | 3.53 | 3.53 |
| 460.87 | 3.11 | 3.11 |
| 533.96 | 3.53 | 3.53 |
| 509.34 | 3.44 | 3.44 |
| 509.34 | 3.44 | 3.44 |
| 512.97 | 3.35 | 3.35 |
| 509.34 | 3.44 | 3.44 |
| 510.88 | 3.07 | 3.07 |
| 558.89 | 3.69 | 3.69 |
| 498.94 | 3.35 | 3.35 |
| 521.90 | 4.48 | 4.48 |
| 488.92 | 3.18 | 3.18 |
| 504.92 | 2.80 | 2.80 |
| 498.92 | 3.76 | 3.76 |
| 504.92 | 2.80 | 2.80 |
| 503.93 | 3.90 | 3.90 |
| 499.97 | 4.34 | 4.34 |
| 488.92 | 3.68 | 3.68 |
| 581.02 | 4.37 | 4.37 |
| 511.98 | 3.87 | 3.87 |
| 503.93 | 3.52 | 3.52 |
| 468.92 | 3.19 | 3.19 |
| 473.91 | 3.89 | 3.89 |
| 580.03 | 5.47 | 5.47 |
| 557.90 | 4.79 | 4.79 |
| 467.93 | 3.94 | 3.94 |
| 487.93 | 4.28 | 4.28 |
| 481.96 | 4.33 | 4.33 |
| 474.95 | 3.25 | 3.25 |
| 509.43 | 4.46 | 4.46 |
| 548.40 | 3.41 | 3.41 |
| 518.36 | 4.00 | 4.00 |
| 494.42 | 3.48 | 3.48 |
| 503.93 | 3.43 | 3.43 |
| 488.92 | 3.05 | 3.05 |
| 504.92 | 2.91 | 2.91 |
| 541.95 | 3.07 | 3.07 |
| 525.02 | 4.04 | 4.04 |
| 531.94 | 3.68 | 3.68 |
| 468.92 | 3.34 | 3.34 |
| 535.97 | 3.12 | 3.12 |
| 525.96 | 3.73 | 3.73 |
| 492.94 | 3.81 | 3.81 |
| 540.90 | 3.39 | 3.39 |
| 581.02 | 4.37 | 4.37 |
| 488.92 | 3.68 | 3.68 |
| 508.35 | 4.55 | 4.55 |
| 493.93 | 3.21 | 3.21 |
| 512.97 | 3.52 | 3.52 |
| 580.03 | 5.47 | 5.47 |
| 512.97 | 3.52 | 3.52 |
| 574.05 | 5.52 | 5.52 |
| 468.92 | 3.19 | 3.19 |
| 468.92 | 3.19 | 3.19 |
| 557.90 | 4.79 | 4.79 |
| 525.96 | 3.73 | 3.73 |
| 525.96 | 3.73 | 3.73 |
| 531.94 | 3.68 | 3.68 |
| 503.93 | 3.25 | 3.25 |
| 468.92 | 3.19 | 3.19 |
| 539.99 | 3.66 | 3.66 |
| 572.33 | 4.54 | 4.54 |
| 474.90 | 3.29 | 3.29 |
| 545.97 | 4.07 | 4.07 |
| 545.97 | 3.61 | 3.61 |
| 468.92 | 3.34 | 3.34 |
| 548.38 | 3.34 | 3.34 |
| 474.90 | 3.29 | 3.29 |
| 468.92 | 3.34 | 3.34 |
| 541.90 | 4.82 | 4.82 |
| 516.98 | 3.43 | 3.43 |
| 483.93 | 2.91 | 2.91 |
| 512.97 | 3.26 | 3.26 |
| 486.45 | 3.77 | 3.77 |
| 460.41 | 3.38 | 3.38 |
| 489.91 | 3.51 | 3.51 |
| 527.88 | 4.43 | 4.43 |
| 504.44 | 3.90 | 3.90 |
| 489.91 | 2.86 | 2.86 |
| 534.36 | 2.97 | 2.97 |
| 503.93 | 3.52 | 3.52 |
| 504.92 | 2.15 | 2.15 |
| 474.95 | 2.75 | 2.75 |
| 511.98 | 4.13 | 4.13 |
| 517.96 | 3.91 | 3.91 |
| 517.96 | 4.08 | 4.08 |
| 517.96 | 4.08 | 4.08 |
| 511.98 | 3.87 | 3.87 |
| 511.98 | 3.87 | 3.87 |
| 489.91 | 1.73 | 1.73 |
| 488.92 | 2.83 | 2.83 |
| 488.92 | 2.83 | 2.83 |
| 490.89 | 2.49 | 2.49 |
| 489.91 | 3.60 | 3.60 |
| 489.91 | 3.60 | 3.60 |
| 503.93 | 3.99 | 3.99 |
| 483.93 | 3.65 | 3.65 |
| 503.93 | 3.99 | 3.99 |
| 483.93 | 3.65 | 3.65 |
| 572.96 | 1.88 | 1.88 |
| 571.97 | 2.98 | 2.98 |
| 565.99 | 3.03 | 3.03 |
| 503.93 | 3.90 | 3.90 |
| 581.02 | 4.87 | 4.87 |
| 582.01 | 4.26 | 4.26 |
| 548.97 | 2.81 | 2.81 |
| 562.96 | 2.34 | 2.34 |
| 548.93 | 2.25 | 2.25 |
| 534.95 | 2.16 | 2.16 |
| 531.94 | 3.52 | 3.52 |
| 525.96 | 3.57 | 3.57 |
| 517.92 | 3.59 | 3.59 |
| 511.94 | 3.64 | 3.64 |
| 531.94 | 3.98 | 3.98 |
| 547.94 | 3.21 | 3.21 |
| 511.94 | 3.64 | 3.64 |
| 624.04 | 5.17 | 5.17 |
| 511.94 | 3.64 | 3.64 |
| 503.93 | 3.38 | 3.38 |
| 517.92 | 3.59 | 3.59 |
| 511.94 | 3.64 | 3.64 |
| 502.95 | 3.22 | 3.22 |
| 484.96 | 3.14 | 3.14 |
| 529.01 | 3.16 | 3.16 |
| 497.95 | 3.33 | 3.33 |
| 498.94 | 2.87 | 2.87 |
| 518.95 | 3.21 | 3.21 |
| 538.02 | 3.83 | 3.83 |
| 538.02 | 3.83 | 3.83 |
| 541.95 | 3.07 | 3.07 |
| 535.97 | 3.12 | 3.12 |
| 489.91 | 2.86 | 2.86 |
| 468.92 | 3.18 | 3.18 |
| 483.93 | 4.41 | 4.41 |
| 519.94 | 2.87 | 2.87 |
| 483.93 | 2.90 | 2.90 |
| 489.91 | 2.99 | 2.99 |
| 469.90 | 2.73 | 2.73 |
| 541.43 | 2.38 | 2.38 |
| 542.42 | 1.77 | 1.77 |
| 505.91 | 2.31 | 2.31 |
| 531.95 | 2.80 | 2.80 |
| 526.95 | 3.12 | 3.12 |
| 511.94 | 2.46 | 2.46 |
| 561.03 | 3.45 | 3.45 |
| 517.92 | 2.14 | 2.14 |
| 556.45 | 2.08 | 2.08 |
| 570.48 | 2.33 | 2.33 |
| 648.55 | 3.85 | 3.85 |
| 512.93 | 3.04 | 3.04 |
| 548.93 | 2.61 | 2.61 |
| 540.04 | 3.83 | 3.83 |
| 520.92 | 1.76 | 1.76 |
| 498.94 | 2.71 | 2.71 |
| 482.94 | 3.73 | 3.73 |
| 482.94 | 3.65 | 3.65 |
| 528.97 | 3.35 | 3.35 |
| 488.92 | 3.60 | 3.60 |
| 469.90 | 2.73 | 2.73 |
| 470.89 | 1.63 | 1.63 |
| 484.92 | 1.94 | 1.94 |
| 484.92 | 2.31 | 2.31 |
| 484.92 | 1.94 | 1.94 |
| 470.89 | 1.63 | 1.63 |
| 469.90 | 2.73 | 2.73 |
| 472.91 | 2.02 | 2.02 |
| 476.92 | 1.54 | 1.54 |
| 518.95 | 3.22 | 3.22 |
| 532.94 | 1.69 | 1.69 |
| 532.94 | 1.69 | 1.69 |
| 520.92 | 1.51 | 1.51 |
| 506.90 | 1.20 | 1.20 |
| 506.90 | 1.20 | 1.20 |
| 520.92 | 1.76 | 1.76 |
| 520.92 | 1.76 | 1.76 |
| 576.03 | 4.31 | 4.31 |
| 532.98 | 3.61 | 3.61 |
| 501.32 | 2.06 | 2.06 |
| 500.33 | 2.66 | 2.66 |
| 515.34 | 2.37 | 2.37 |
| 529.37 | 2.62 | 2.62 |
| 444.50 | 2.04 | 2.04 |
| 447.50 | 1.68 | 1.68 |
| 461.50 | 2.78 | 2.78 |
| 484.92 | 2.02 | 2.02 |
| 483.93 | 2.92 | 2.92 |
| 499.93 | 2.27 | 2.27 |
| 512.97 | 3.37 | 3.37 |
| 507.95 | 3.63 | 3.63 |
| 504.92 | 2.91 | 2.91 |
| 504.92 | 2.91 | 2.91 |
| 505.91 | 2.31 | 2.31 |
| 516.51 | 3.10 | 3.10 |
| 532.96 | 3.62 | 3.62 |
| 516.51 | 3.10 | 3.10 |
| 513.53 | 2.67 | 2.67 |
| 533.95 | 3.01 | 3.01 |
| 526.95 | 3.12 | 3.12 |
| 490.90 | 2.14 | 2.14 |
| 504.93 | 2.45 | 2.45 |
| 469.90 | 2.23 | 2.23 |
| 498.95 | 2.50 | 2.50 |
| 484.92 | 1.94 | 1.94 |
| 498.95 | 2.25 | 2.25 |
| 512.97 | 2.81 | 2.81 |
| 534.95 | 1.77 | 1.77 |
| 484.92 | 2.19 | 2.19 |
| 552.92 | 3.21 | 3.21 |
| 510.96 | 2.51 | 2.51 |
| 524.98 | 3.07 | 3.07 |
| 484.92 | 2.19 | 2.19 |
| 470.89 | 1.63 | 1.63 |
| 512.93 | 3.04 | 3.04 |
| 486.89 | 0.87 | 0.87 |
| 500.92 | 1.43 | 1.43 |
| 511.41 | 2.75 | 2.75 |
| 506.42 | 2.20 | 2.20 |
| 562.48 | 3.69 | 3.69 |
| 505.43 | 3.30 | 3.30 |
| 534.47 | 2.76 | 2.76 |
| 520.44 | 2.50 | 2.50 |
| 536.44 | 2.20 | 2.20 |
| 540.45 | 2.71 | 2.71 |
| 520.44 | 2.50 | 2.50 |
| 534.47 | 2.81 | 2.81 |
| 612.54 | 4.27 | 4.27 |
| 546.48 | 3.07 | 3.07 |
| 507.40 | 1.59 | 1.59 |
| 517.50 | 2.50 | 2.50 |
| 532.96 | 3.62 | 3.62 |
| 520.44 | 2.50 | 2.50 |
| 506.42 | 2.20 | 2.20 |
| 548.45 | 3.60 | 3.60 |
| 536.44 | 1.74 | 1.74 |
| 484.31 | 1.32 | 1.32 |
| 487.44 | 2.50 | 2.50 |
| 488.43 | 1.90 | 1.90 |
| 455.88 | 2.56 | 2.56 |
| 473.42 | 1.57 | 1.57 |
| 472.43 | 2.68 | 2.68 |
| 498.34 | 1.62 | 1.62 |
| 512.37 | 1.88 | 1.88 |
| 483.33 | 2.42 | 2.42 |
| 519.46 | 3.19 | 3.19 |
| 520.44 | 2.59 | 2.59 |
| 489.31 | 1.87 | 1.87 |
| 483.33 | 2.42 | 2.42 |
| 483.33 | 2.42 | 2.42 |
| 489.36 | 1.98 | 1.98 |
| 512.37 | 1.93 | 1.93 |
| 497.35 | 2.31 | 2.31 |
| 483.33 | 1.78 | 1.78 |
| 498.34 | 1.62 | 1.62 |
| 590.44 | 3.39 | 3.39 |
| 517.77 | 2.57 | 2.57 |
| 482.34 | 3.02 | 3.02 |
| 482.34 | 3.02 | 3.02 |
| 483.33 | 2.42 | 2.42 |
| 482.34 | 2.53 | 2.53 |
| 519.33 | 1.50 | 1.50 |
| 536.33 | 2.24 | 2.24 |
| 518.34 | 2.60 | 2.60 |
| 483.33 | 3.36 | 3.36 |
| 483.33 | 3.22 | 3.22 |
| 489.31 | 3.31 | 3.31 |
| 509.61 | 2.64 | 2.64 |
| 455.52 | 1.33 | 1.33 |
| 495.46 | 1.62 | 1.62 |
| 473.42 | 2.07 | 2.07 |
| 573.50 | 4.20 | 4.20 |
| 604.56 | 4.46 | 4.46 |
| 474.44 | 3.27 | 3.27 |
| 473.45 | 4.37 | 4.37 |
| 474.44 | 3.64 | 3.64 |
| 468.92 | 2.84 | 2.84 |
| 482.94 | 3.90 | 3.90 |
| 505.43 | 2.80 | 2.80 |
| 483.33 | 1.92 | 1.92 |
| 578.52 | 3.93 | 3.93 |
| 491.90 | 3.84 | 3.84 |
| 513.35 | 1.28 | 1.28 |
| 527.98 | 3.95 | 3.95 |
| 498.94 | 2.70 | 2.70 |
| 475.43 | 4.10 | 4.10 |
| 498.94 | 3.77 | 3.77 |
| 499.93 | 3.03 | 3.03 |
| 498.94 | 2.54 | 2.54 |
| 469.90 | 3.67 | 3.67 |
| 475.43 | 3.57 | 3.57 |
| 530.35 | 2.03 | 2.03 |
| 497.95 | 3.30 | 3.30 |
| 512.37 | 2.01 | 2.01 |
| 498.94 | 2.57 | 2.57 |
| 513.96 | 3.69 | 3.69 |
| 535.45 | 2.16 | 2.16 |
| 532.00 | 3.35 | 3.35 |
| 475.88 | 2.68 | 2.68 |