Basic Information
ID: ALA3705998
Type: Binding
Description: Biological Assay: The EnzoLyte 520 Generic MMP Assay Kit (AnaSpec Inc.) can detect the activity of several MMPs including MMP-1, 2, 3, 7, 8, 9, 13, and 14. This kit uses a 5-FAM/QXL 520 fluorescence resonance energy transfer (FRET) peptide as an MMP substrate. In the intact FRET peptide, the fluorescence of 5-FAM is quenched by QXL 520. Upon cleavage into two separate fragments by MMPs, the fluorescence of 5-FAM is recovered, and can be monitored at excitation/emission wavelengths=490 nm/520 nm. The assays are performed in a convenient 96-well or 384-well microplate format.
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA3705998
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 403.44 | 3.07 | 3.07 |
| 419.44 | 2.36 | 2.36 |
| 446.46 | 3.37 | 3.37 |
| 460.49 | 3.30 | 3.30 |
| 414.47 | 4.04 | 4.04 |
| 456.46 | 3.56 | 3.56 |
| 453.46 | 4.22 | 4.22 |
| 467.49 | 4.52 | 4.52 |
| 456.46 | 3.85 | 3.85 |
| 429.44 | 2.84 | 2.84 |
| 416.45 | 2.89 | 2.89 |
| 413.44 | 3.55 | 3.55 |
| 414.43 | 2.94 | 2.94 |
| 413.44 | 3.55 | 3.55 |
| 403.40 | 3.14 | 3.14 |
| 443.46 | 4.03 | 4.03 |
| 451.49 | 4.26 | 4.26 |
| 452.47 | 3.65 | 3.65 |
| 417.43 | 3.45 | 3.45 |
| 418.42 | 2.85 | 2.85 |
| 438.45 | 3.42 | 3.42 |
| 420.47 | 3.38 | 3.38 |
| 414.43 | 2.94 | 2.94 |
| 428.46 | 3.13 | 3.13 |
| 454.49 | 3.60 | 3.60 |
| 452.47 | 3.65 | 3.65 |
| 422.45 | 2.37 | 2.37 |
| 437.46 | 4.03 | 4.03 |
| 418.48 | 4.22 | 4.22 |
| 403.44 | 3.37 | 3.37 |
| 412.45 | 4.15 | 4.15 |
| 419.47 | 3.61 | 3.61 |
| 428.46 | 3.13 | 3.13 |
| 469.48 | 4.40 | 4.40 |
| 413.44 | 3.55 | 3.55 |
| 406.45 | 3.13 | 3.13 |
| 451.49 | 4.26 | 4.26 |
| 402.41 | 3.75 | 3.75 |
| 413.44 | 3.25 | 3.25 |
| 443.47 | 2.69 | 2.69 |
| 406.45 | 3.13 | 3.13 |
| 447.89 | 3.91 | 3.91 |
| 435.49 | 2.29 | 2.29 |
| 406.45 | 3.13 | 3.13 |
| 420.47 | 3.52 | 3.52 |
| 452.47 | 3.65 | 3.65 |
| 430.44 | 4.29 | 4.29 |
| 439.48 | 4.12 | 4.12 |
| 436.47 | 2.50 | 2.50 |
| 403.41 | 2.27 | 2.27 |
| 421.43 | 3.51 | 3.51 |
| 404.43 | 2.76 | 2.76 |
| 376.42 | 3.36 | 3.36 |
| 416.45 | 2.59 | 2.59 |
| 419.47 | 3.31 | 3.31 |
| 437.46 | 3.73 | 3.73 |
| 322.33 | 2.32 | 2.32 |
| 350.38 | 2.97 | 2.97 |
| 410.44 | 3.91 | 3.91 |
| 424.46 | 4.22 | 4.22 |
| 432.51 | 4.78 | 4.78 |
| 417.43 | 2.58 | 2.58 |
| 441.50 | 4.36 | 4.36 |
| 510.48 | 4.75 | 4.75 |
| 403.40 | 2.84 | 2.84 |
| 414.43 | 2.94 | 2.94 |
| 417.43 | 3.15 | 3.15 |
| 362.39 | 3.12 | 3.12 |
| 412.45 | 3.86 | 3.86 |
| 430.44 | 4.00 | 4.00 |
| 402.41 | 3.45 | 3.45 |
| 482.52 | 5.31 | 5.31 |
| 416.44 | 3.02 | 3.02 |
| 410.44 | 3.91 | 3.91 |
| 341.37 | 3.22 | 3.22 |
| 443.46 | 2.97 | 2.97 |
| 418.48 | 3.92 | 3.92 |
| 402.41 | 3.45 | 3.45 |
| 469.48 | 4.40 | 4.40 |
| 404.43 | 2.76 | 2.76 |
| 474.52 | 3.39 | 3.39 |
| 399.41 | 3.07 | 3.07 |
| 483.50 | 4.71 | 4.71 |
| 405.46 | 4.62 | 4.62 |
| 390.45 | 3.85 | 3.85 |
| 419.47 | 3.31 | 3.31 |
| 447.47 | 3.71 | 3.71 |
| 400.44 | 3.73 | 3.73 |
| 419.47 | 3.31 | 3.31 |
| 404.43 | 2.76 | 2.76 |
| 406.45 | 3.13 | 3.13 |
| 376.42 | 3.46 | 3.46 |
| 420.47 | 3.08 | 3.08 |
| 416.45 | 2.59 | 2.59 |
| 444.47 | 4.07 | 4.07 |
| 416.45 | 2.59 | 2.59 |
| 337.34 | 2.71 | 2.71 |