Kinase-Glo End-Point Assay: The IC50 values for PKCl-diMeO and compounds described herein and illustrated in FIG. 6 are described in Table 2. The IC50...

Basic Information

ID: ALA3706117

Type: Binding

Description: Kinase-Glo End-Point Assay: The IC50 values for PKCl-diMeO and compounds described herein and illustrated in FIG. 6 are described in Table 2. The IC50 values were determined using a Kinase-Glo end-point assay with 125 ng/ml aPKCζ, 25 μM CREBtide, and 0.1 μM ATP.

Format: BAO_0000357

Organism: Homo sapiens

Target: Protein kinase C zeta(ALA3438)

Document: ALA3638452

BindingDB Source: 6568

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA3706117

IC50

Total(8)

Parent Molecular Weight	ALogP	Polar Surface Area
233.29	2.78	2.78
321.40	3.58	3.58
265.31	3.31	3.31
292.32	3.08	3.08
312.19	3.55	3.55
281.76	3.83	3.83
365.84	4.41	4.41

Parent Molecular Weight

ALogP

Polar Surface Area

233.29

2.78

321.40

3.58

265.31

3.31

292.32

3.08

312.19

3.55

281.76

3.83

365.84

4.41

Kinase-Glo End-Point Assay: The IC50 values for PKCl-diMeO and compounds described herein and illustrated in FIG. 6 are described in Table 2. The IC50...

Basic Information

Activity Charts

Compound Summary