Basic Information
ID: ALA3706208
Type: Binding
Description: Radioligand Binding Assay: Compound potency can be assessed by a radioligand binding assay (described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-1430) in which the inhibition constant (Ki) is determined in membranes prepared from CHO cells expressing either the orexin-1 (OX1) or orexin-2 (OX2) receptor.
Organism: Rattus norvegicus
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA3706208
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 413.48 | 3.89 | 3.89 |
| 431.47 | 4.03 | 4.03 |
| 426.52 | 4.23 | 4.23 |
| 403.44 | 3.48 | 3.48 |