Basic Information
ID: ALA3706223
Type: Binding
Description: Inhibition Assay: In addition, the dipeptidyl peptidase-IV (DPPIV) assay herein was applied to investigate the DPPIV inhibitory activity of the prepared compounds as described above. The method of the DPPIV assay was described in Lin et al., 1998. Inhibition of dipeptidyl peptidase IV by fluoroolefin-containing N-peptidyl-O-hydroxylamine peptidomimetics. Proc. Natl. Acad. Sci. USA Vol. 95, pp. 14020-14024.
Organism: Hepatitis C virus genotype 1a (isolate H)
Activity Charts
Bioactivity
Activity Types for Assay ALA3706223
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 685.90 | 1.47 | 1.47 |
| 361.44 | 3.01 | 3.01 |
| 395.46 | 3.20 | 3.20 |
| 335.36 | 0.95 | 0.95 |
| 458.56 | 3.00 | 3.00 |
| 492.57 | 3.19 | 3.19 |
| 432.47 | 0.94 | 0.94 |
| 329.40 | 3.46 | 3.46 |