Assay Report Card

Basic Information

ID: ALA3707492

Type: Binding

Description: Enzyme Inhibition Assay: Heterocyclic analogs of propargyl-linked inhibitors of the third generation analogs were evaluated in enzyme inhibition assays, assessed for S. aureus and S. pyogenes inhibition, and evaluated for mammalian cell toxicity.

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
372.474.094.09
386.504.404.40
328.423.463.46
358.453.473.47
358.453.473.47
367.451.951.95
359.433.183.18
373.463.433.43
359.432.872.87
358.453.783.78
359.432.872.87
372.474.034.03
329.412.862.86
329.412.862.86
330.402.252.25