Basic Information
ID: ALA3707534
Type: Binding
Description: Enzyme Assay: The molecules are tested in dose-response studies on the following enzymes MMP1, MMP3, MMP9, ADAMS and ADAM10 according to the same protocol as that described for the TACE enzyme in example 28 but with different substrates (MMP R&D system reference: P126-990 and ADAM R&D system reference: ES003).
Activity Charts
Bioactivity
Activity Types for Assay ALA3707534
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 414.51 | 0.45 | 0.45 |
| 438.51 | -0.73 | -0.73 |
| 541.63 | 1.30 | 1.30 |
| 596.61 | 3.35 | 3.35 |