Enzyme Assay: The molecules are tested in dose-response studies on the following enzymes MMP1, MMP3, MMP9, ADAMS and ADAM10 according to the same prot...

Basic Information

ID: ALA3707536

Type: Binding

Description: Enzyme Assay: The molecules are tested in dose-response studies on the following enzymes MMP1, MMP3, MMP9, ADAMS and ADAM10 according to the same protocol as that described for the TACE enzyme in example 28 but with different substrates (MMP R&D system reference: P126-990 and ADAM R&D system reference: ES003).

Format: BAO_0000357

Target: Matrix metalloproteinase 3(ALA283)

Document: ALA3639220

BindingDB Source: 7111

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA3707536

IC50

Total(4)

Parent Molecular Weight	ALogP	Polar Surface Area
414.51	0.45	0.45
438.51	-0.73	-0.73
541.63	1.30	1.30
596.61	3.35	3.35

Parent Molecular Weight

ALogP

Polar Surface Area

414.51

0.45

438.51

-0.73

541.63

1.30

596.61

3.35

Enzyme Assay: The molecules are tested in dose-response studies on the following enzymes MMP1, MMP3, MMP9, ADAMS and ADAM10 according to the same prot...

Basic Information

Activity Charts

Compound Summary