Basic Information
ID: ALA3707549
Type: Binding
Description: Inhibition Assay: The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et al. 2006 J. Biol. Chem. (7)).
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3707549
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 585.01 | 2.78 | 2.78 |
| 474.47 | 0.46 | 0.46 |
| 565.65 | 3.20 | 3.20 |
| 455.90 | 3.43 | 3.43 |
| 585.01 | 2.78 | 2.78 |
| 585.01 | 2.78 | 2.78 |
| 585.01 | 2.78 | 2.78 |
| 570.99 | 2.39 | 2.39 |
| 570.99 | 2.39 | 2.39 |
| 556.96 | 2.00 | 2.00 |
| 555.03 | 3.41 | 3.41 |
| 599.04 | 3.17 | 3.17 |
| 613.07 | 3.26 | 3.26 |
| 345.36 | 1.11 | 1.11 |
| 506.56 | 2.67 | 2.67 |
| 536.54 | 1.74 | 1.74 |
| 492.53 | 2.28 | 2.28 |
| 522.51 | 1.35 | 1.35 |
| 549.58 | 1.53 | 1.53 |
| 549.58 | 1.53 | 1.53 |
| 548.60 | 0.93 | 0.93 |
| 492.53 | 2.28 | 2.28 |
| 474.47 | -0.62 | -0.62 |
| 474.47 | 0.46 | 0.46 |
| 475.46 | -0.15 | -0.15 |
| 490.54 | 0.93 | 0.93 |
| 499.52 | 1.60 | 1.60 |
| 513.55 | 1.38 | 1.38 |
| 507.54 | 1.20 | 1.20 |
| 533.32 | 0.41 | 0.41 |
| 485.50 | 0.26 | 0.26 |
| 487.51 | 0.20 | 0.20 |
| 489.49 | 0.16 | 0.16 |
| 447.52 | 0.87 | 0.87 |
| 428.49 | 1.14 | 1.14 |
| 446.53 | 1.47 | 1.47 |
| 445.54 | 2.08 | 2.08 |
| 496.59 | 2.63 | 2.63 |
| 439.51 | 2.02 | 2.02 |
| 438.53 | 1.42 | 1.42 |
| 395.50 | 2.56 | 2.56 |
| 482.58 | 1.73 | 1.73 |
| 469.49 | 1.08 | 1.08 |
| 517.58 | 2.55 | 2.55 |
| 425.49 | 1.63 | 1.63 |
| 491.55 | 1.57 | 1.57 |
| 441.48 | 0.60 | 0.60 |
| 467.57 | 2.65 | 2.65 |
| 480.56 | 3.35 | 3.35 |
| 488.54 | 3.90 | 3.90 |
| 498.54 | 1.05 | 1.05 |
| 499.52 | 1.18 | 1.18 |
| 484.51 | 1.92 | 1.92 |
| 527.53 | 1.17 | 1.17 |
| 517.97 | 2.12 | 2.12 |
| 552.41 | 2.78 | 2.78 |
| 513.55 | 1.48 | 1.48 |
| 513.55 | 0.96 | 0.96 |
| 559.62 | 3.14 | 3.14 |
| 558.64 | 2.54 | 2.54 |
| 558.68 | 3.40 | 3.40 |
| 545.59 | 2.75 | 2.75 |
| 593.68 | 4.22 | 4.22 |
| 501.58 | 3.29 | 3.29 |
| 567.65 | 3.24 | 3.24 |
| 517.58 | 2.27 | 2.27 |
| 543.66 | 4.32 | 4.32 |
| 556.66 | 5.02 | 5.02 |
| 564.64 | 5.57 | 5.57 |
| 558.68 | 3.40 | 3.40 |
| 545.59 | 2.75 | 2.75 |
| 593.68 | 4.22 | 4.22 |
| 501.58 | 3.29 | 3.29 |
| 567.65 | 3.24 | 3.24 |
| 517.58 | 2.27 | 2.27 |
| 543.66 | 4.32 | 4.32 |
| 489.55 | 1.53 | 1.53 |
| 488.57 | 0.93 | 0.93 |
| 488.61 | 1.80 | 1.80 |
| 475.52 | 1.14 | 1.14 |
| 523.61 | 2.62 | 2.62 |
| 431.51 | 1.69 | 1.69 |
| 497.58 | 1.63 | 1.63 |
| 447.51 | 0.66 | 0.66 |
| 473.60 | 2.71 | 2.71 |
| 486.59 | 3.41 | 3.41 |
| 494.57 | 3.96 | 3.96 |
| 503.58 | 1.84 | 1.84 |
| 565.65 | 3.20 | 3.20 |
| 622.73 | 3.81 | 3.81 |
| 503.58 | 1.84 | 1.84 |
| 564.66 | 2.60 | 2.60 |
| 564.66 | 2.60 | 2.60 |
| 551.62 | 2.81 | 2.81 |
| 551.62 | 2.81 | 2.81 |
| 579.68 | 3.29 | 3.29 |
| 579.68 | 3.59 | 3.59 |
| 573.68 | 3.30 | 3.30 |
| 570.67 | 5.63 | 5.63 |
| 503.58 | 1.84 | 1.84 |
| 623.68 | 2.90 | 2.90 |
| 565.65 | 3.20 | 3.20 |
| 436.53 | 3.85 | 3.85 |