Assay Report Card

Basic Information

ID: ALA3707567

Type: Binding

Description: Binding Assay: The affinities of selected Purine Derivatives for the adenosine A1 receptor were determined by measuring the displacement of specific [3H] 2-chloro-N6-cyclopentyl adenosine binding in CHO cells stably transfected with human recombinant A1 adenosine receptor expressed as Ki (nM).

Organism: Homo sapiens

Cell type: CHO

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
312.24-1.76-1.76
380.360.010.01
414.810.660.66
382.33-1.15-1.15
346.69-1.11-1.11
399.43-0.31-0.31