Basic Information
ID: ALA3707646
Type: Binding
Description: Inhibition Assay: The kinase activity of all three JAK kinases is measured using a radioactive, end-point assay and with trace amounts of 33P-ATP.
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3707646
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 372.45 | 1.86 | 1.86 |
| 414.54 | 2.88 | 2.88 |
| 428.56 | 3.27 | 3.27 |
| 397.46 | 1.75 | 1.75 |
| 428.56 | 3.13 | 3.13 |
| 373.44 | 1.25 | 1.25 |
| 388.46 | 0.83 | 0.83 |
| 389.44 | 0.54 | 0.54 |
| 460.56 | 1.43 | 1.43 |
| 458.55 | 0.82 | 0.82 |
| 458.55 | 1.09 | 1.09 |
| 471.59 | 1.00 | 1.00 |
| 373.44 | 1.25 | 1.25 |
| 372.45 | 1.86 | 1.86 |
| 322.37 | 2.05 | 2.05 |
| 338.37 | 2.27 | 2.27 |
| 358.43 | 1.47 | 1.47 |
| 336.40 | 2.44 | 2.44 |
| 352.40 | 2.66 | 2.66 |
| 336.40 | 2.44 | 2.44 |
| 322.37 | 2.05 | 2.05 |
| 338.37 | 2.27 | 2.27 |
| 358.43 | 1.47 | 1.47 |
| 350.43 | 2.83 | 2.83 |
| 366.43 | 3.05 | 3.05 |
| 386.48 | 2.25 | 2.25 |
| 400.51 | 2.63 | 2.63 |
| 372.45 | 1.86 | 1.86 |
| 386.48 | 2.25 | 2.25 |
| 386.48 | 2.24 | 2.24 |
| 400.51 | 2.49 | 2.49 |
| 336.40 | 2.44 | 2.44 |
| 350.43 | 2.83 | 2.83 |
| 350.43 | 2.69 | 2.69 |
| 364.45 | 3.08 | 3.08 |
| 386.48 | 2.10 | 2.10 |
| 414.54 | 2.88 | 2.88 |
| 414.54 | 2.88 | 2.88 |
| 414.54 | 2.88 | 2.88 |
| 350.43 | 2.75 | 2.75 |
| 386.48 | 2.16 | 2.16 |
| 376.39 | 3.46 | 3.46 |
| 400.51 | 2.55 | 2.55 |
| 426.55 | 2.94 | 2.94 |
| 442.59 | 3.58 | 3.58 |
| 386.48 | 2.25 | 2.25 |
| 412.52 | 2.64 | 2.64 |
| 384.87 | 3.40 | 3.40 |
| 460.99 | 3.60 | 3.60 |
| 386.48 | 1.87 | 1.87 |
| 373.44 | 1.25 | 1.25 |
| 401.50 | 2.03 | 2.03 |
| 415.52 | 2.28 | 2.28 |
| 400.51 | 2.64 | 2.64 |
| 414.54 | 2.65 | 2.65 |
| 428.56 | 2.89 | 2.89 |
| 401.50 | 2.03 | 2.03 |
| 415.52 | 2.28 | 2.28 |
| 337.39 | 1.84 | 1.84 |
| 372.45 | 1.86 | 1.86 |
| 350.43 | 2.45 | 2.45 |
| 415.52 | 2.28 | 2.28 |
| 414.54 | 2.88 | 2.88 |
| 336.40 | 2.44 | 2.44 |
| 397.46 | 1.73 | 1.73 |
| 386.48 | 2.16 | 2.16 |
| 412.52 | 2.73 | 2.73 |
| 406.90 | 2.51 | 2.51 |
| 430.53 | 1.85 | 1.85 |
| 388.45 | 0.83 | 0.83 |
| 401.50 | 1.70 | 1.70 |
| 429.55 | 2.53 | 2.53 |
| 415.52 | 2.28 | 2.28 |
| 430.54 | 1.86 | 1.86 |
| 458.59 | 2.34 | 2.34 |
| 493.62 | 1.68 | 1.68 |
| 461.62 | 3.00 | 3.00 |
| 500.63 | 2.11 | 2.11 |
| 419.54 | 1.97 | 1.97 |
| 416.51 | 1.32 | 1.32 |
| 441.52 | 1.19 | 1.19 |
| 489.67 | 3.78 | 3.78 |
| 403.47 | 1.26 | 1.26 |
| 407.89 | 1.90 | 1.90 |
| 417.50 | 1.65 | 1.65 |
| 432.51 | 0.66 | 0.66 |
| 446.54 | 1.31 | 1.31 |
| 408.49 | 2.45 | 2.45 |
| 460.56 | 1.43 | 1.43 |
| 506.61 | 0.49 | 0.49 |
| 486.60 | 1.87 | 1.87 |
| 431.53 | 0.62 | 0.62 |
| 513.63 | 1.34 | 1.34 |
| 460.56 | 1.43 | 1.43 |
| 485.62 | 1.76 | 1.76 |
| 541.73 | 2.81 | 2.81 |
| 499.65 | 1.78 | 1.78 |
| 398.45 | 1.12 | 1.12 |
| 458.55 | 0.82 | 0.82 |
| 453.53 | 1.21 | 1.21 |
| 495.61 | 2.75 | 2.75 |
| 534.65 | 1.97 | 1.97 |
| 514.61 | 1.94 | 1.94 |
| 465.54 | 2.39 | 2.39 |
| 459.58 | 1.22 | 1.22 |
| 485.62 | 1.39 | 1.39 |
| 485.62 | 1.39 | 1.39 |
| 513.67 | 2.03 | 2.03 |
| 527.70 | 2.27 | 2.27 |
| 510.63 | 1.14 | 1.14 |
| 485.62 | 1.25 | 1.25 |
| 440.45 | 2.64 | 2.64 |
| 482.53 | 3.67 | 3.67 |
| 389.46 | 2.58 | 2.58 |
| 403.49 | 2.82 | 2.82 |
| 411.49 | 2.00 | 2.00 |
| 415.42 | 3.74 | 3.74 |