Basic Information
ID: ALA3707781
Type: Binding
Description: ATP Depletion Assay: The activity of PIM1, PIM2, and PIM3 is measured using a luciferase-luciferin based ATP detection reagent to quantify ATP depletion resulting from kinase-catalyzed phosphoryl transfer to a peptide substrate.
Format: BAO_0000357
Organism: Homo sapiens
Target: Serine/threonine-protein kinase PIM2(ALA4523)
Document: ALA3638421
BindingDB Source: 6059
Activity Charts
Bioactivity
Activity Types for Assay ALA3707781
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 472.47 | 2.54 | 2.54 |
| 457.46 | 2.96 | 2.96 |
| 441.45 | 5.08 | 5.08 |
| 454.48 | 3.58 | 3.58 |
| 406.46 | 4.23 | 4.23 |
| 424.45 | 4.36 | 4.36 |
| 452.51 | 5.00 | 5.00 |
| 468.52 | 5.74 | 5.74 |
| 444.43 | 4.94 | 4.94 |
| 466.53 | 4.44 | 4.44 |
| 427.52 | 3.06 | 3.06 |
| 466.53 | 4.44 | 4.44 |
| 452.51 | 4.19 | 4.19 |
| 436.51 | 5.22 | 5.22 |
| 440.47 | 5.11 | 5.11 |
| 450.53 | 5.47 | 5.47 |
| 471.48 | 3.27 | 3.27 |
| 439.47 | 2.82 | 2.82 |
| 439.47 | 2.82 | 2.82 |
| 454.50 | 5.35 | 5.35 |
| 437.49 | 3.90 | 3.90 |
| 452.51 | 4.18 | 4.18 |
| 452.51 | 4.18 | 4.18 |
| 442.44 | 4.50 | 4.50 |
| 424.45 | 4.36 | 4.36 |
| 420.49 | 4.47 | 4.47 |
| 438.48 | 4.61 | 4.61 |
| 420.49 | 4.47 | 4.47 |
| 438.48 | 4.61 | 4.61 |
| 438.48 | 4.61 | 4.61 |
| 470.50 | 4.32 | 4.32 |
| 438.48 | 3.94 | 3.94 |
| 456.47 | 4.75 | 4.75 |
| 438.48 | 4.61 | 4.61 |
| 470.50 | 4.32 | 4.32 |
| 438.48 | 4.61 | 4.61 |
| 486.49 | 4.02 | 4.02 |
| 426.44 | 4.80 | 4.80 |
| 454.50 | 5.43 | 5.43 |
| 456.47 | 4.01 | 4.01 |
| 455.48 | 4.63 | 4.63 |
| 438.48 | 3.88 | 3.88 |
| 412.51 | 3.87 | 3.87 |
| 426.54 | 4.12 | 4.12 |
| 412.51 | 3.87 | 3.87 |
| 422.48 | 4.91 | 4.91 |
| 418.52 | 5.07 | 5.07 |
| 436.51 | 5.21 | 5.21 |
| 440.47 | 5.04 | 5.04 |
| 440.47 | 5.04 | 5.04 |
| 404.49 | 4.77 | 4.77 |
| 422.48 | 4.91 | 4.91 |
| 482.53 | 4.42 | 4.42 |
| 457.46 | 3.35 | 3.35 |
| 439.47 | 3.21 | 3.21 |
| 497.55 | 4.00 | 4.00 |
| 479.56 | 3.86 | 3.86 |
| 440.47 | 5.04 | 5.04 |
| 440.47 | 5.04 | 5.04 |
| 452.51 | 4.18 | 4.18 |
| 438.48 | 3.88 | 3.88 |
| 440.47 | 5.04 | 5.04 |
| 426.44 | 4.80 | 4.80 |
| 406.46 | 3.49 | 3.49 |
| 456.47 | 4.01 | 4.01 |
| 424.45 | 3.63 | 3.63 |
| 442.44 | 3.77 | 3.77 |
| 423.56 | 3.56 | 3.56 |
| 410.54 | 5.15 | 5.15 |
| 437.45 | 3.12 | 3.12 |
| 437.45 | 3.12 | 3.12 |
| 453.49 | 3.46 | 3.46 |
| 453.49 | 3.46 | 3.46 |
| 426.44 | 4.80 | 4.80 |
| 441.46 | 4.38 | 4.38 |
| 481.50 | 3.78 | 3.78 |
| 454.48 | 2.40 | 2.40 |
| 439.47 | 3.21 | 3.21 |
| 393.54 | 4.34 | 4.34 |
| 472.49 | 5.62 | 5.62 |
| 506.48 | 5.46 | 5.46 |
| 509.45 | 5.17 | 5.17 |
| 464.51 | 5.69 | 5.69 |
| 457.46 | 2.96 | 2.96 |
| 440.45 | 2.85 | 2.85 |
| 440.45 | 2.85 | 2.85 |
| 457.45 | 4.05 | 4.05 |
| 440.45 | 2.21 | 2.21 |
| 422.46 | 2.07 | 2.07 |
| 472.47 | 3.63 | 3.63 |
| 484.52 | 5.44 | 5.44 |
| 456.47 | 4.75 | 4.75 |
| 506.48 | 4.89 | 4.89 |
| 456.47 | 4.75 | 4.75 |
| 458.46 | 5.18 | 5.18 |
| 471.48 | 3.60 | 3.60 |
| 471.48 | 3.60 | 3.60 |
| 456.47 | 4.01 | 4.01 |
| 424.46 | 3.64 | 3.64 |
| 458.46 | 4.99 | 4.99 |