Basic Information
ID: ALA3707890
Type: Binding
Description: Binding Assay: 5-HT1D binding assays (agonist radioligand)were performed using bovine caudate membranes according to the methods of Heuring and Peroutka (J. Neurosci 1987, 7: 894-903). 5-HT1B (rat cerebral cortex) binding assays (agonist radioligand) were performed according to the method of Hoyer et. al. (Eur. J. Pharmacol. 1995, 118: 1-12).
Format: BAO_0000221
Organism: Rattus norvegicus
Tissue: Cerebral cortex
Target: Serotonin 1b (5-HT1b) receptor(ALA3459)
Document: ALA3638726
BindingDB Source: 6054
Activity Charts
Bioactivity
Activity Types for Assay ALA3707890
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 295.41 | 1.32 | 1.32 |
| 336.46 | 3.99 | 3.99 |
| 338.48 | 3.90 | 3.90 |
| 338.48 | 3.90 | 3.90 |
| 324.45 | 3.69 | 3.69 |
| 308.38 | 3.22 | 3.22 |