Basic Information
ID: ALA3720754
Type: Functional
Description: Antagonist activity against human P2X2/3 receptor expressed in CHOK1 cells assessed as inhibition of alpha,beta-meATP-induced calcium response incubated for 20 mins by Fluo-3AM dye based FLIPR assay
Organism: Homo sapiens
Cell type: CHO-K1
Activity Charts
Bioactivity
Activity Types for Assay ALA3720754
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 451.49 | 3.98 | 3.98 |
| 451.49 | 4.24 | 4.24 |
| 403.44 | 3.06 | 3.06 |
| 450.50 | 3.97 | 3.97 |
| 449.51 | 4.31 | 4.31 |
| 449.51 | 4.56 | 4.56 |
| 411.50 | 3.80 | 3.80 |
| 379.46 | 3.93 | 3.93 |
| 397.48 | 3.15 | 3.15 |
| 445.52 | 4.32 | 4.32 |
| 445.52 | 4.07 | 4.07 |
| 437.46 | 3.67 | 3.67 |
| 451.49 | 3.98 | 3.98 |
| 437.46 | 3.67 | 3.67 |
| 383.45 | 2.90 | 2.90 |
| 431.50 | 4.07 | 4.07 |
| 431.50 | 3.82 | 3.82 |
| 431.50 | 4.07 | 4.07 |
| 431.50 | 3.82 | 3.82 |
| 415.50 | 3.85 | 3.85 |
| 415.50 | 3.60 | 3.60 |
| 429.48 | 3.57 | 3.57 |
| 452.48 | 2.51 | 2.51 |
| 431.50 | 3.82 | 3.82 |
| 451.49 | 3.98 | 3.98 |
| 451.49 | 3.98 | 3.98 |
| 396.49 | 3.75 | 3.75 |
| 444.54 | 4.92 | 4.92 |
| 444.54 | 4.67 | 4.67 |
| 378.47 | 4.54 | 4.54 |
| 444.54 | 4.92 | 4.92 |
| 414.48 | 3.89 | 3.89 |
| 462.53 | 5.06 | 5.06 |
| 462.53 | 4.81 | 4.81 |
| 396.46 | 4.67 | 4.67 |
| 450.50 | 4.84 | 4.84 |
| 450.50 | 4.59 | 4.59 |
| 448.53 | 4.91 | 4.91 |
| 448.53 | 5.16 | 5.16 |