Basic Information
ID: ALA3720755
Type: Functional
Description: Antagonist activity against rat P2X3 receptor expressed in CHOK1 cells assessed as inhibition of alpha,beta-meATP-induced calcium response incubated for 20 mins by Fluo-3AM dye based FLIPR assay
Organism: Rattus norvegicus
Cell type: CHO-K1
Activity Charts
Bioactivity
Activity Types for Assay ALA3720755
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 465.56 | 5.00 | 5.00 |
| 438.54 | 4.89 | 4.89 |
| 431.54 | 4.49 | 4.49 |
| 444.58 | 5.34 | 5.34 |
| 396.53 | 4.17 | 4.17 |
| 430.55 | 4.95 | 4.95 |
| 416.53 | 4.56 | 4.56 |
| 414.51 | 4.33 | 4.33 |
| 460.58 | 5.56 | 5.56 |
| 472.57 | 4.38 | 4.38 |
| 446.55 | 5.31 | 5.31 |
| 430.55 | 4.95 | 4.95 |
| 418.50 | 4.54 | 4.54 |
| 368.48 | 3.39 | 3.39 |
| 472.59 | 4.72 | 4.72 |
| 402.50 | 4.54 | 4.54 |
| 458.56 | 4.33 | 4.33 |
| 479.97 | 4.18 | 4.18 |
| 437.93 | 4.45 | 4.45 |
| 430.55 | 4.95 | 4.95 |
| 444.58 | 5.34 | 5.34 |
| 444.58 | 5.34 | 5.34 |
| 382.50 | 3.78 | 3.78 |
| 394.52 | 3.93 | 3.93 |
| 442.56 | 5.10 | 5.10 |
| 422.55 | 5.05 | 5.05 |
| 422.55 | 5.05 | 5.05 |
| 392.46 | 4.27 | 4.27 |
| 408.52 | 4.74 | 4.74 |
| 402.49 | 4.68 | 4.68 |
| 403.48 | 4.07 | 4.07 |
| 408.54 | 4.95 | 4.95 |
| 430.55 | 5.30 | 5.30 |
| 454.93 | 5.47 | 5.47 |
| 504.94 | 6.35 | 6.35 |
| 409.51 | 4.14 | 4.14 |
| 483.57 | 5.64 | 5.64 |
| 421.50 | 4.28 | 4.28 |
| 422.55 | 5.05 | 5.05 |
| 420.51 | 3.72 | 3.72 |
| 407.47 | 3.98 | 3.98 |
| 438.55 | 4.75 | 4.75 |
| 368.48 | 3.80 | 3.80 |
| 423.56 | 3.49 | 3.49 |
| 388.47 | 3.93 | 3.93 |
| 402.50 | 4.32 | 4.32 |
| 418.50 | 3.55 | 3.55 |
| 432.52 | 3.94 | 3.94 |
| 452.52 | 4.42 | 4.42 |
| 466.55 | 4.81 | 4.81 |
| 480.57 | 5.05 | 5.05 |
| 450.97 | 5.22 | 5.22 |
| 456.59 | 5.49 | 5.49 |
| 382.50 | 3.78 | 3.78 |
| 402.92 | 4.04 | 4.04 |
| 436.94 | 4.65 | 4.65 |
| 437.93 | 4.41 | 4.41 |
| 434.52 | 4.70 | 4.70 |
| 386.47 | 3.53 | 3.53 |
| 420.49 | 4.14 | 4.14 |
| 499.62 | 4.16 | 4.16 |
| 402.50 | 4.00 | 4.00 |
| 437.37 | 5.04 | 5.04 |
| 471.39 | 5.56 | 5.56 |
| 404.46 | 4.02 | 4.02 |
| 438.48 | 4.53 | 4.53 |
| 437.93 | 4.30 | 4.30 |
| 423.90 | 3.74 | 3.74 |
| 389.88 | 3.13 | 3.13 |
| 417.51 | 3.96 | 3.96 |
| 417.51 | 3.70 | 3.70 |
| 369.47 | 2.79 | 2.79 |
| 445.52 | 3.08 | 3.08 |