Inhibition of N-terminal GST-tagged human recombinant PASK kinase domain (879 to 1323 residues) expressed in insect cells using MBP protein substrate ...

Basic Information

ID: ALA3720757

Type: Binding

Description: Inhibition of N-terminal GST-tagged human recombinant PASK kinase domain (879 to 1323 residues) expressed in insect cells using MBP protein substrate incubated for 120 mins in presence of [33P]ATP by scintillation counting based radiochemical assay

Format: BAO_0000219

Organism: Homo sapiens

Target: PAS domain-containing serine/threonine-protein kinase(ALA6054)

Document: ALA3714726

Inhibition of N-terminal GST-tagged human recombinant PASK kinase domain (879 to 1323 residues) expressed in insect cells using MBP protein substrate incubated for 120 mins in presence of [33P]ATP by scintillation counting based radiochemical assay: 38

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA3720757

IC50

Total(50)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
365.41	4.51	4.51
373.41	4.73	4.73
359.39	4.34	4.34
379.39	4.72	4.72
395.85	5.24	5.24
377.44	4.16	4.16
377.47	5.05	5.05
375.43	4.02	4.02
379.39	4.72	4.72
405.43	5.26	5.26
427.41	4.70	4.70
390.47	4.59	4.59
387.44	5.10	5.10
407.47	5.34	5.34
377.38	4.48	4.48
361.40	3.51	3.51
358.40	4.07	4.07
388.43	3.70	3.70
421.43	4.50	4.50
393.42	5.12	5.12
386.46	4.86	4.86
393.42	5.12	5.12
386.46	4.77	4.77
374.44	4.63	4.63
387.44	5.10	5.10
310.36	3.17	3.17
375.43	4.89	4.89
374.44	4.63	4.63
377.40	3.71	3.71
400.48	5.16	5.16
372.43	4.38	4.38
389.42	3.57	3.57
353.40	4.37	4.37
367.38	3.36	3.36
419.38	5.06	5.06
353.40	4.37	4.37
379.44	4.90	4.90
353.40	4.37	4.37
393.46	5.29	5.29
339.37	3.98	3.98
369.37	4.26	4.26
383.40	4.65	4.65
355.37	3.68	3.68
365.41	4.51	4.51
367.42	4.76	4.76
351.38	4.12	4.12
357.36	4.12	4.12
369.37	4.26	4.26
378.43	3.80	3.80
351.38	4.12	4.12