Basic Information
ID: ALA3720849
Type: Binding
Description: Inhibition of human KIAA1361 kinase domain (2 to 322 residues) expressed in baculovirus assessed as remaining ATP level incubated for 2 hrs by luciferase-luciferin coupled chemiluminescent kinase assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3720849
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 394.52 | 4.18 | 4.18 |
| 444.53 | 3.95 | 3.95 |
| 417.30 | 3.14 | 3.14 |
| 412.53 | 4.84 | 4.84 |
| 426.56 | 4.71 | 4.71 |
| 408.54 | 4.57 | 4.57 |
| 467.61 | 5.41 | 5.41 |
| 422.57 | 4.96 | 4.96 |
| 408.54 | 4.05 | 4.05 |
| 392.54 | 4.73 | 4.73 |
| 378.52 | 4.34 | 4.34 |
| 406.57 | 5.12 | 5.12 |
| 538.65 | 4.44 | 4.44 |
| 509.65 | 5.88 | 5.88 |
| 494.98 | 3.41 | 3.41 |
| 452.52 | 3.33 | 3.33 |
| 523.63 | 5.12 | 5.12 |
| 394.52 | 3.66 | 3.66 |
| 428.53 | 4.06 | 4.06 |
| 442.56 | 4.81 | 4.81 |
| 489.62 | 4.93 | 4.93 |
| 463.41 | 4.94 | 4.94 |
| 511.63 | 3.49 | 3.49 |
| 449.38 | 4.72 | 4.72 |
| 446.13 | 3.57 | 3.57 |
| 489.58 | 6.16 | 6.16 |
| 380.49 | 3.79 | 3.79 |
| 368.43 | 2.38 | 2.38 |
| 364.49 | 3.95 | 3.95 |
| 550.66 | 5.32 | 5.32 |
| 422.40 | 3.27 | 3.27 |
| 440.59 | 5.69 | 5.69 |
| 394.52 | 3.67 | 3.67 |
| 372.85 | 3.03 | 3.03 |
| 450.62 | 5.59 | 5.59 |
| 422.57 | 4.44 | 4.44 |
| 489.55 | 4.35 | 4.35 |
| 465.34 | 5.21 | 5.21 |
| 455.54 | 3.06 | 3.06 |
| 457.54 | 2.45 | 2.45 |
| 438.55 | 2.36 | 2.36 |
| 401.42 | 3.57 | 3.57 |
| 351.45 | 3.56 | 3.56 |
| 384.48 | 4.28 | 4.28 |
| 358.44 | 3.76 | 3.76 |
| 392.38 | 3.51 | 3.51 |
| 359.43 | 3.16 | 3.16 |
| 459.39 | 5.04 | 5.04 |
| 400.48 | 4.40 | 4.40 |
| 390.53 | 4.66 | 4.66 |
| 414.51 | 4.19 | 4.19 |
| 372.47 | 3.96 | 3.96 |
| 364.49 | 4.09 | 4.09 |
| 441.36 | 5.27 | 5.27 |
| 524.67 | 4.52 | 4.52 |
| 324.38 | 2.32 | 2.32 |
| 384.48 | 4.19 | 4.19 |
| 393.49 | 2.45 | 2.45 |
| 407.47 | 3.11 | 3.11 |
| 398.51 | 4.23 | 4.23 |
| 412.53 | 4.84 | 4.84 |
| 413.47 | 2.00 | 2.00 |
| 488.57 | 3.92 | 3.92 |
| 445.54 | 4.90 | 4.90 |
| 430.50 | 3.60 | 3.60 |
| 426.56 | 5.18 | 5.18 |
| 408.50 | 5.44 | 5.44 |
| 427.55 | 3.99 | 3.99 |
| 370.50 | 4.64 | 4.64 |
| 374.44 | 2.80 | 2.80 |
| 375.43 | 3.27 | 3.27 |
| 427.55 | 4.39 | 4.39 |
| 399.49 | 4.67 | 4.67 |
| 386.50 | 4.27 | 4.27 |
| 386.50 | 4.00 | 4.00 |
| 412.53 | 4.84 | 4.84 |
| 391.52 | 3.60 | 3.60 |
| 386.50 | 4.52 | 4.52 |
| 440.47 | 4.98 | 4.98 |
| 359.43 | 3.16 | 3.16 |
| 455.56 | 3.86 | 3.86 |
| 362.47 | 3.49 | 3.49 |
| 400.52 | 4.91 | 4.91 |
| 426.50 | 2.63 | 2.63 |
| 412.47 | 2.18 | 2.18 |
| 359.43 | 3.48 | 3.48 |
| 359.43 | 3.48 | 3.48 |
| 343.47 | 2.17 | 2.17 |
| 391.52 | 3.92 | 3.92 |
| 458.54 | 3.91 | 3.91 |
| 392.50 | 2.71 | 2.71 |
| 408.48 | 2.76 | 2.76 |
| 422.51 | 3.07 | 3.07 |
| 489.56 | 3.32 | 3.32 |
| 513.64 | 5.25 | 5.25 |
| 413.52 | 3.61 | 3.61 |
| 417.49 | 4.50 | 4.50 |
| 474.54 | 3.62 | 3.62 |