Basic Information
ID: ALA3720908
Type: Functional
Description: Agonist activity at human T1R1/T1R3 expressed in HEK293T cells co-expressing Galpha15 assessed as enhancement of MSG-induced calcium mobilization by measuring ratio of MSG EC50 in presence and absence of 1 uM compound by fluo-4-AM dye based FLIPR assay
Organism: Homo sapiens
Cell type: HEK-293T
Activity Charts
Bioactivity
Activity Types for Assay ALA3720908
Ratio EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 339.44 | 3.85 | 3.85 |
| 284.33 | 4.02 | 4.02 |
| 266.34 | 3.01 | 3.01 |
| 275.39 | 3.51 | 3.51 |
| 285.41 | 3.90 | 3.90 |
| 251.40 | 3.85 | 3.85 |
| 247.34 | 3.01 | 3.01 |
| 263.34 | 2.25 | 2.25 |
| 268.79 | 4.43 | 4.43 |
| 323.22 | 5.27 | 5.27 |
| 280.80 | 4.43 | 4.43 |
| 300.79 | 4.54 | 4.54 |
| 297.35 | 3.21 | 3.21 |
| 265.35 | 3.10 | 3.10 |
| 281.36 | 3.51 | 3.51 |
| 277.37 | 4.14 | 4.14 |
| 297.35 | 3.21 | 3.21 |
| 319.79 | 3.85 | 3.85 |
| 299.75 | 2.42 | 2.42 |
| 297.35 | 3.17 | 3.17 |
| 279.29 | 1.49 | 1.49 |
| 288.19 | 3.74 | 3.74 |
| 237.34 | 3.60 | 3.60 |
| 258.37 | 3.87 | 3.87 |
| 239.38 | 3.76 | 3.76 |
| 271.38 | 3.86 | 3.86 |
| 231.29 | 3.35 | 3.35 |
| 319.36 | 2.76 | 2.76 |
| 289.38 | 4.14 | 4.14 |
| 261.32 | 3.36 | 3.36 |
| 340.21 | 4.65 | 4.65 |