Assay Report Card

Basic Information

ID: ALA3720938

Type: Functional

Description: Agonist activity at human T1R1/T1R3 expressed in HEK293T cells co-expressing Galpha15 assessed as enhancement of MSG-induced calcium mobilization by measuring ratio of MSG EC50 in presence and absence of 0.3 uM compound by fluo-4-AM dye based FLIPR assay

Organism: Homo sapiens

Cell type: HEK-293T

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
275.393.793.79
247.343.013.01
251.403.853.85
292.383.403.40
276.383.793.79
301.773.773.77
245.374.034.03
263.383.783.78
267.343.533.53
281.743.243.24