Basic Information
ID: ALA3720938
Type: Functional
Description: Agonist activity at human T1R1/T1R3 expressed in HEK293T cells co-expressing Galpha15 assessed as enhancement of MSG-induced calcium mobilization by measuring ratio of MSG EC50 in presence and absence of 0.3 uM compound by fluo-4-AM dye based FLIPR assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK-293T
Target: T1R1/T1R3(ALA3832641)
Document: ALA3714709
Agonist activity at human T1R1/T1R3 expressed in HEK293T cells co-expressing Galpha15 assessed as enhancement of MSG-induced calcium mobilization by measuring ratio of MSG EC50 in presence and absence of 0.3 uM compound by fluo-4-AM dye based FLIPR assay: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA3720938
Ratio EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 275.39 | 3.79 | 3.79 |
| 247.34 | 3.01 | 3.01 |
| 251.40 | 3.85 | 3.85 |
| 292.38 | 3.40 | 3.40 |
| 276.38 | 3.79 | 3.79 |
| 301.77 | 3.77 | 3.77 |
| 245.37 | 4.03 | 4.03 |
| 263.38 | 3.78 | 3.78 |
| 267.34 | 3.53 | 3.53 |
| 281.74 | 3.24 | 3.24 |