Basic Information
ID: ALA3720941
Type: Functional
Description: Agonist activity at human T1R2/T1R3 expressed in HEK293T cells co-expressing Galpha15 assessed as calcium mobilization by fluo-4-AM dye based FLIPR assay
Organism: Homo sapiens
Cell type: HEK-293T
Activity Charts
Bioactivity
Activity Types for Assay ALA3720941
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 297.20 | 3.15 | 3.15 |
| 261.35 | 3.09 | 3.09 |
| 266.34 | 3.59 | 3.59 |
| 312.37 | 3.29 | 3.29 |
| 297.38 | 3.54 | 3.54 |
| 283.66 | 3.58 | 3.58 |
| 326.18 | 4.26 | 4.26 |
| 251.33 | 2.51 | 2.51 |
| 303.30 | 4.00 | 4.00 |
| 269.75 | 3.79 | 3.79 |
| 320.22 | 4.80 | 4.80 |
| 315.80 | 4.10 | 4.10 |
| 300.79 | 4.24 | 4.24 |
| 309.72 | 3.75 | 3.75 |
| 324.21 | 4.87 | 4.87 |
| 269.34 | 3.82 | 3.82 |
| 345.24 | 4.61 | 4.61 |
| 297.31 | 3.45 | 3.45 |
| 274.27 | 3.51 | 3.51 |
| 297.31 | 3.45 | 3.45 |
| 292.26 | 3.65 | 3.65 |
| 252.32 | 3.54 | 3.54 |
| 272.74 | 3.89 | 3.89 |
| 272.74 | 3.89 | 3.89 |
| 307.18 | 4.54 | 4.54 |
| 268.32 | 3.24 | 3.24 |
| 321.21 | 4.58 | 4.58 |
| 277.33 | 3.15 | 3.15 |
| 265.78 | 3.96 | 3.96 |
| 253.29 | 3.27 | 3.27 |
| 245.37 | 3.61 | 3.61 |
| 273.34 | 1.79 | 1.79 |
| 314.14 | 4.39 | 4.39 |
| 359.73 | 4.63 | 4.63 |
| 324.21 | 4.87 | 4.87 |
| 325.67 | 3.60 | 3.60 |
| 310.18 | 4.56 | 4.56 |
| 309.13 | 4.26 | 4.26 |
| 291.14 | 4.12 | 4.12 |
| 273.76 | 4.52 | 4.52 |
| 303.30 | 4.15 | 4.15 |
| 245.37 | 3.61 | 3.61 |
| 300.23 | 4.55 | 4.55 |
| 236.29 | 2.53 | 2.53 |
| 245.37 | 3.67 | 3.67 |
| 247.34 | 3.01 | 3.01 |
| 263.23 | 2.94 | 2.94 |
| 305.31 | 4.11 | 4.11 |
| 259.31 | 2.53 | 2.53 |
| 263.34 | 2.71 | 2.71 |
| 277.43 | 3.74 | 3.74 |
| 335.32 | 3.87 | 3.87 |
| 260.16 | 3.91 | 3.91 |
| 300.23 | 4.55 | 4.55 |
| 267.32 | 3.52 | 3.52 |
| 293.22 | 3.76 | 3.76 |
| 277.26 | 3.33 | 3.33 |
| 330.26 | 4.56 | 4.56 |
| 259.39 | 4.06 | 4.06 |
| 273.42 | 4.17 | 4.17 |
| 287.75 | 3.46 | 3.46 |
| 281.40 | 4.46 | 4.46 |
| 269.75 | 3.79 | 3.79 |
| 286.20 | 4.30 | 4.30 |
| 311.22 | 3.40 | 3.40 |
| 252.75 | 3.04 | 3.04 |
| 265.78 | 3.96 | 3.96 |
| 275.24 | 3.22 | 3.22 |
| 285.31 | 4.01 | 4.01 |
| 303.30 | 4.15 | 4.15 |
| 291.29 | 3.72 | 3.72 |
| 303.30 | 4.15 | 4.15 |
| 286.20 | 4.30 | 4.30 |
| 291.29 | 3.86 | 3.86 |
| 346.25 | 4.32 | 4.32 |
| 259.39 | 3.92 | 3.92 |
| 316.23 | 4.31 | 4.31 |
| 291.29 | 3.72 | 3.72 |
| 286.20 | 4.30 | 4.30 |
| 282.77 | 3.05 | 3.05 |
| 301.28 | 3.47 | 3.47 |
| 235.33 | 2.46 | 2.46 |
| 317.33 | 4.11 | 4.11 |
| 266.77 | 3.29 | 3.29 |
| 289.27 | 3.61 | 3.61 |
| 350.25 | 4.81 | 4.81 |
| 283.33 | 2.91 | 2.91 |
| 313.35 | 2.91 | 2.91 |
| 283.35 | 3.94 | 3.94 |
| 345.83 | 4.16 | 4.16 |
| 331.21 | 3.65 | 3.65 |
| 285.77 | 4.15 | 4.15 |
| 301.77 | 3.85 | 3.85 |
| 297.35 | 3.15 | 3.15 |
| 269.32 | 3.63 | 3.63 |
| 283.33 | 2.91 | 2.91 |
| 256.31 | 2.79 | 2.79 |
| 256.31 | 2.79 | 2.79 |
| 277.26 | 3.33 | 3.33 |
| 291.29 | 3.72 | 3.72 |
| 301.31 | 3.89 | 3.89 |
| 301.77 | 3.85 | 3.85 |
| 317.77 | 3.56 | 3.56 |
| 315.80 | 4.41 | 4.41 |
| 331.80 | 3.86 | 3.86 |
| 270.33 | 3.04 | 3.04 |
| 281.36 | 3.45 | 3.45 |
| 313.35 | 2.91 | 2.91 |
| 270.33 | 3.35 | 3.35 |
| 286.33 | 2.80 | 2.80 |
| 299.80 | 4.46 | 4.46 |
| 279.38 | 4.11 | 4.11 |