Basic Information
ID: ALA3720975
Type: Binding
Description: Inhibition of N-terminal GST-tagged human recombinant PASK kinase domain (879 to 1323 residues) expressed in insect cells using MBP protein substrate incubated for 120 mins in presence of [33P]ATP by scintillation counting based radiochemical assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3720975
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 313.32 | 2.62 | 2.62 |
| 355.36 | 3.41 | 3.41 |
| 347.31 | 2.16 | 2.16 |
| 359.35 | 2.03 | 2.03 |
| 374.36 | 1.61 | 1.61 |
| 376.37 | 2.80 | 2.80 |
| 378.34 | 2.19 | 2.19 |
| 377.36 | 2.07 | 2.07 |
| 356.34 | 1.26 | 1.26 |
| 345.79 | 2.06 | 2.06 |
| 365.40 | 1.60 | 1.60 |
| 352.36 | 0.68 | 0.68 |
| 362.78 | 3.28 | 3.28 |
| 377.80 | 2.86 | 2.86 |
| 337.34 | 1.10 | 1.10 |
| 329.32 | 2.02 | 2.02 |
| 360.37 | 2.71 | 2.71 |
| 399.41 | 2.60 | 2.60 |
| 357.38 | 2.59 | 2.59 |
| 343.35 | 2.21 | 2.21 |
| 351.37 | 1.29 | 1.29 |
| 365.40 | 1.30 | 1.30 |
| 345.32 | 1.73 | 1.73 |
| 344.34 | 1.61 | 1.61 |
| 321.32 | 2.47 | 2.47 |
| 350.31 | 2.62 | 2.62 |
| 355.76 | 3.13 | 3.13 |
| 360.37 | 3.04 | 3.04 |
| 328.34 | 2.63 | 2.63 |
| 343.35 | 2.21 | 2.21 |
| 368.30 | 3.07 | 3.07 |
| 375.39 | 2.91 | 2.91 |
| 377.38 | 3.58 | 3.58 |
| 389.37 | 2.44 | 2.44 |
| 337.77 | 2.99 | 2.99 |
| 347.33 | 2.06 | 2.06 |
| 361.36 | 2.10 | 2.10 |
| 344.33 | 3.20 | 3.20 |
| 354.37 | 1.60 | 1.60 |
| 378.82 | 3.27 | 3.27 |
| 416.44 | 2.73 | 2.73 |
| 360.37 | 2.71 | 2.71 |
| 336.78 | 3.59 | 3.59 |
| 322.30 | 2.60 | 2.60 |
| 318.34 | 2.76 | 2.76 |
| 345.36 | 3.01 | 3.01 |
| 344.33 | 3.20 | 3.20 |
| 346.35 | 2.39 | 2.39 |
| 346.35 | 2.39 | 2.39 |
| 338.75 | 3.11 | 3.11 |
| 343.34 | 3.81 | 3.81 |
| 357.20 | 4.06 | 4.06 |
| 306.30 | 2.89 | 2.89 |
| 338.75 | 3.11 | 3.11 |
| 364.36 | 2.47 | 2.47 |
| 344.37 | 2.86 | 2.86 |
| 415.45 | 3.12 | 3.12 |
| 413.36 | 4.15 | 4.15 |
| 314.35 | 2.85 | 2.85 |
| 312.29 | 0.56 | 0.56 |
| 294.27 | 1.33 | 1.33 |
| 348.36 | 2.77 | 2.77 |
| 348.36 | 2.77 | 2.77 |
| 322.75 | 3.41 | 3.41 |
| 402.41 | 2.39 | 2.39 |
| 395.42 | 0.85 | 0.85 |
| 382.38 | 0.93 | 0.93 |
| 361.36 | 2.83 | 2.83 |
| 362.35 | 2.23 | 2.23 |
| 348.32 | 2.19 | 2.19 |
| 330.35 | 2.69 | 2.69 |
| 329.36 | 3.29 | 3.29 |
| 327.34 | 4.10 | 4.10 |
| 330.35 | 2.69 | 2.69 |
| 326.36 | 3.84 | 3.84 |
| 328.33 | 3.50 | 3.50 |
| 375.38 | 3.14 | 3.14 |
| 306.30 | 2.89 | 2.89 |
| 320.33 | 3.20 | 3.20 |
| 393.83 | 3.97 | 3.97 |
| 393.83 | 3.97 | 3.97 |
| 366.42 | 4.14 | 4.14 |
| 318.34 | 2.76 | 2.76 |
| 297.36 | 2.96 | 2.96 |
| 354.41 | 4.07 | 4.07 |