Basic Information
ID: ALA3721013
Type: Functional
Description: Antagonist activity against human CXCR5 expressed in RBL cells assessed as inhibition of human CXCL13-induced intracellular Ca2+ level by fluo-4/AM dye based FLIPR assay
Organism: Homo sapiens
Cell type: RBL
Activity Charts
Bioactivity
Activity Types for Assay ALA3721013
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 351.40 | 2.91 | 2.91 |
| 353.42 | 3.13 | 3.13 |
| 365.43 | 3.28 | 3.28 |
| 365.43 | 3.14 | 3.14 |
| 367.45 | 3.52 | 3.52 |
| 371.82 | 3.26 | 3.26 |
| 438.28 | 4.42 | 4.42 |
| 337.44 | 2.86 | 2.86 |
| 444.34 | 3.68 | 3.68 |
| 442.32 | 3.46 | 3.46 |
| 368.41 | 2.14 | 2.14 |
| 335.40 | 2.92 | 2.92 |
| 331.37 | 3.19 | 3.19 |
| 349.36 | 3.33 | 3.33 |
| 375.42 | 3.59 | 3.59 |
| 332.36 | 2.59 | 2.59 |
| 332.36 | 2.59 | 2.59 |
| 333.35 | 1.98 | 1.98 |
| 320.35 | 2.52 | 2.52 |
| 320.35 | 2.52 | 2.52 |
| 339.35 | 1.81 | 1.81 |
| 357.34 | 2.04 | 2.04 |
| 336.39 | 2.40 | 2.40 |
| 369.49 | 3.60 | 3.60 |
| 365.43 | 2.93 | 2.93 |
| 403.40 | 3.94 | 3.94 |
| 353.39 | 3.06 | 3.06 |
| 387.50 | 3.81 | 3.81 |
| 381.47 | 3.75 | 3.75 |
| 383.44 | 3.14 | 3.14 |
| 421.42 | 4.15 | 4.15 |
| 371.41 | 3.27 | 3.27 |
| 433.43 | 4.30 | 4.30 |
| 383.42 | 3.42 | 3.42 |
| 360.41 | 2.79 | 2.79 |
| 378.43 | 2.02 | 2.02 |
| 379.41 | 2.62 | 2.62 |
| 378.43 | 3.01 | 3.01 |
| 396.44 | 2.23 | 2.23 |
| 397.43 | 2.83 | 2.83 |
| 390.44 | 3.15 | 3.15 |
| 408.45 | 2.38 | 2.38 |
| 409.44 | 2.98 | 2.98 |
| 367.45 | 3.48 | 3.48 |
| 361.44 | 3.50 | 3.50 |
| 363.46 | 4.16 | 4.16 |
| 365.47 | 4.08 | 4.08 |
| 377.48 | 4.55 | 4.55 |
| 379.50 | 4.64 | 4.64 |
| 361.44 | 3.91 | 3.91 |
| 363.46 | 4.00 | 4.00 |
| 349.43 | 3.77 | 3.77 |
| 351.45 | 3.55 | 3.55 |
| 361.44 | 3.77 | 3.77 |
| 363.46 | 3.69 | 3.69 |
| 375.47 | 4.30 | 4.30 |
| 335.40 | 3.38 | 3.38 |
| 337.42 | 3.30 | 3.30 |
| 363.46 | 4.16 | 4.16 |
| 367.42 | 3.91 | 3.91 |
| 369.44 | 3.68 | 3.68 |
| 379.43 | 4.05 | 4.05 |
| 353.39 | 3.52 | 3.52 |
| 355.41 | 3.44 | 3.44 |
| 385.41 | 4.05 | 4.05 |
| 387.43 | 3.82 | 3.82 |
| 373.40 | 3.58 | 3.58 |
| 369.44 | 3.68 | 3.68 |
| 369.44 | 3.68 | 3.68 |
| 385.41 | 4.05 | 4.05 |
| 385.41 | 4.05 | 4.05 |
| 383.88 | 4.42 | 4.42 |
| 403.40 | 4.48 | 4.48 |