Basic Information
ID: ALA3721014
Type: Functional
Description: Antagonist activity against human lung GPR34 expressed in CHO cells co-expressing Galpha116 assessed as inhibition of lysophosphatidyl serine-induced increase in intracellular calcium level pre-incubated before lysophosphatidyl serine addition and measured after 180 secs by Fluo 3-AM dye based fluorescent assay
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA3721014
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 459.93 | 4.19 | 4.19 |
| 530.00 | 6.01 | 6.01 |
| 518.03 | 5.93 | 5.93 |
| 538.04 | 5.83 | 5.83 |
| 555.06 | 6.69 | 6.69 |
| 512.01 | 5.87 | 5.87 |
| 540.02 | 7.07 | 7.07 |
| 546.04 | 7.13 | 7.13 |
| 543.98 | 6.10 | 6.10 |
| 529.98 | 6.66 | 6.66 |
| 497.98 | 6.08 | 6.08 |
| 530.00 | 6.01 | 6.01 |
| 530.00 | 6.01 | 6.01 |
| 536.02 | 6.07 | 6.07 |
| 527.02 | 5.45 | 5.45 |
| 527.02 | 5.45 | 5.45 |
| 542.06 | 7.23 | 7.23 |
| 542.06 | 7.23 | 7.23 |
| 583.68 | 7.50 | 7.50 |
| 560.05 | 7.37 | 7.37 |
| 531.63 | 6.31 | 6.31 |
| 540.02 | 7.07 | 7.07 |
| 525.99 | 6.76 | 6.76 |
| 517.59 | 5.74 | 5.74 |
| 556.08 | 6.89 | 6.89 |
| 553.01 | 5.85 | 5.85 |
| 541.00 | 6.34 | 6.34 |
| 525.99 | 6.76 | 6.76 |
| 541.00 | 6.34 | 6.34 |
| 543.98 | 6.90 | 6.90 |
| 525.99 | 7.20 | 7.20 |
| 543.98 | 6.90 | 6.90 |
| 540.02 | 7.07 | 7.07 |
| 525.00 | 6.49 | 6.49 |
| 539.03 | 6.50 | 6.50 |
| 525.00 | 6.49 | 6.49 |
| 539.03 | 6.50 | 6.50 |
| 525.99 | 5.89 | 5.89 |
| 543.98 | 6.03 | 6.03 |
| 512.01 | 6.41 | 6.41 |
| 512.01 | 6.41 | 6.41 |
| 525.99 | 5.66 | 5.66 |
| 532.02 | 5.72 | 5.72 |
| 526.98 | 5.05 | 5.05 |
| 525.01 | 5.69 | 5.69 |
| 543.98 | 5.80 | 5.80 |
| 543.98 | 5.80 | 5.80 |
| 525.99 | 5.66 | 5.66 |
| 525.99 | 5.66 | 5.66 |
| 543.98 | 5.80 | 5.80 |
| 540.02 | 6.00 | 6.00 |
| 550.02 | 5.46 | 5.46 |
| 551.01 | 4.86 | 4.86 |
| 526.98 | 5.05 | 5.05 |
| 509.54 | 5.15 | 5.15 |
| 592.66 | 5.80 | 5.80 |
| 603.10 | 4.65 | 4.65 |
| 525.99 | 5.66 | 5.66 |
| 525.99 | 5.66 | 5.66 |
| 540.02 | 5.97 | 5.97 |
| 540.02 | 5.97 | 5.97 |
| 556.02 | 5.57 | 5.57 |
| 553.02 | 5.56 | 5.56 |
| 560.44 | 6.31 | 6.31 |
| 552.03 | 6.16 | 6.16 |
| 531.61 | 5.82 | 5.82 |
| 549.63 | 5.79 | 5.79 |
| 546.00 | 4.86 | 4.86 |
| 543.98 | 5.80 | 5.80 |
| 543.98 | 5.80 | 5.80 |
| 540.02 | 6.00 | 6.00 |
| 538.63 | 5.03 | 5.03 |
| 525.99 | 5.66 | 5.66 |
| 519.60 | 5.12 | 5.12 |
| 540.02 | 5.97 | 5.97 |
| 533.56 | 4.88 | 4.88 |
| 560.44 | 6.31 | 6.31 |
| 551.00 | 5.53 | 5.53 |
| 554.05 | 6.22 | 6.22 |