Basic Information
ID: ALA3721017
Type: Functional
Description: Antagonist activity against chimpanzee GPR105 expressed in stable HEK cells co-expressing chimeric G-protein Gqi5 assessed as inhibition of UDP-glucose-induced Ca2+ signaling response incubated for 20 mins by FLIPR assay
Organism: Pan troglodytes
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA3721017
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 412.49 | 6.31 | 6.31 |
| 388.49 | 6.46 | 6.46 |
| 406.48 | 6.60 | 6.60 |
| 414.40 | 6.83 | 6.83 |
| 490.40 | 7.49 | 7.49 |
| 490.40 | 7.49 | 7.49 |
| 472.41 | 7.19 | 7.19 |
| 475.51 | 7.36 | 7.36 |
| 509.49 | 7.60 | 7.60 |
| 491.51 | 6.46 | 6.46 |
| 478.44 | 7.25 | 7.25 |
| 463.77 | 7.81 | 7.81 |
| 430.31 | 6.55 | 6.55 |
| 429.32 | 7.15 | 7.15 |
| 414.40 | 6.26 | 6.26 |
| 426.47 | 6.10 | 6.10 |
| 460.55 | 5.80 | 5.80 |
| 476.50 | 6.36 | 6.36 |
| 450.51 | 6.89 | 6.89 |
| 412.87 | 6.64 | 6.64 |
| 459.43 | 6.68 | 6.68 |
| 454.47 | 6.63 | 6.63 |
| 422.40 | 6.31 | 6.31 |
| 414.46 | 5.70 | 5.70 |
| 440.54 | 6.63 | 6.63 |
| 412.49 | 5.89 | 5.89 |
| 442.46 | 7.17 | 7.17 |
| 424.50 | 6.60 | 6.60 |
| 473.78 | 7.26 | 7.26 |
| 398.46 | 6.11 | 6.11 |
| 426.47 | 6.13 | 6.13 |
| 426.90 | 6.95 | 6.95 |
| 457.74 | 7.74 | 7.74 |
| 410.47 | 6.21 | 6.21 |
| 396.41 | 6.12 | 6.12 |
| 492.50 | 6.24 | 6.24 |
| 518.23 | 7.37 | 7.37 |
| 490.40 | 7.33 | 7.33 |
| 508.39 | 7.63 | 7.63 |
| 462.88 | 7.52 | 7.52 |