Basic Information
ID: ALA3721140
Type: Functional
Description: Antagonist activity against PAR4 in human platelet rich plasma assessed as inhibition of gamma-thrombin-induced platelet aggregation pre-incubated for 5 mins before gamma-thrombin addition by microplate aggregation assay
Organism: Homo sapiens
Tissue: Plasma
Activity Charts
Bioactivity
Activity Types for Assay ALA3721140
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 532.59 | 6.55 | 6.55 |
| 514.59 | 4.25 | 4.25 |
| 542.64 | 5.03 | 5.03 |
| 530.60 | 5.54 | 5.54 |
| 570.65 | 4.76 | 4.76 |
| 582.58 | 5.27 | 5.27 |
| 588.59 | 6.05 | 6.05 |
| 542.54 | 6.39 | 6.39 |
| 502.59 | 6.24 | 6.24 |
| 623.03 | 6.71 | 6.71 |
| 609.73 | 5.26 | 5.26 |
| 505.58 | 5.63 | 5.63 |
| 534.62 | 5.72 | 5.72 |
| 526.00 | 5.97 | 5.97 |
| 568.66 | 5.33 | 5.33 |
| 443.51 | 4.15 | 4.15 |
| 539.64 | 4.93 | 4.93 |
| 513.60 | 4.40 | 4.40 |
| 555.64 | 4.60 | 4.60 |
| 589.70 | 6.19 | 6.19 |
| 495.54 | 5.22 | 5.22 |
| 414.47 | 4.26 | 4.26 |
| 561.65 | 5.63 | 5.63 |
| 605.70 | 5.64 | 5.64 |
| 600.68 | 5.83 | 5.83 |
| 513.60 | 4.48 | 4.48 |
| 509.54 | 5.46 | 5.46 |
| 608.70 | 4.62 | 4.62 |
| 645.76 | 6.06 | 6.06 |
| 506.58 | 6.95 | 6.95 |
| 507.62 | 6.03 | 6.03 |
| 495.54 | 6.41 | 6.41 |
| 471.34 | 5.26 | 5.26 |
| 502.98 | 6.82 | 6.82 |
| 512.55 | 5.89 | 5.89 |
| 520.62 | 3.61 | 3.61 |
| 520.62 | 4.24 | 4.24 |
| 498.57 | 5.50 | 5.50 |
| 465.54 | 3.92 | 3.92 |
| 532.63 | 4.92 | 4.92 |
| 491.57 | 5.09 | 5.09 |
| 447.52 | 4.71 | 4.71 |
| 522.59 | 6.72 | 6.72 |
| 512.60 | 6.25 | 6.25 |
| 519.53 | 6.52 | 6.52 |
| 515.57 | 6.69 | 6.69 |
| 587.11 | 6.48 | 6.48 |
| 540.63 | 6.85 | 6.85 |
| 560.68 | 4.80 | 4.80 |
| 475.57 | 5.48 | 5.48 |
| 475.57 | 5.48 | 5.48 |
| 504.62 | 4.64 | 4.64 |
| 435.51 | 4.56 | 4.56 |
| 516.56 | 6.08 | 6.08 |
| 567.68 | 5.53 | 5.53 |
| 600.68 | 5.91 | 5.91 |
| 587.68 | 6.16 | 6.16 |
| 615.62 | 6.22 | 6.22 |
| 600.68 | 5.91 | 5.91 |
| 482.47 | 5.28 | 5.28 |
| 490.57 | 5.92 | 5.92 |
| 502.57 | 4.42 | 4.42 |
| 491.55 | 5.32 | 5.32 |
| 474.50 | 4.38 | 4.38 |
| 474.50 | 4.38 | 4.38 |
| 508.56 | 6.06 | 6.06 |
| 520.59 | 5.93 | 5.93 |
| 491.55 | 5.32 | 5.32 |