Basic Information
ID: ALA3721176
Type: Functional
Description: Inverse agonist activity at rat G-protein GSalpha fused GPR6 (unknown origin) expressed in HEK293 cell membranes assessed as cAMP accumulation pre-incubated for 30 mins by microbeta plate reader based assay1
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: G-protein coupled receptor 6(ALA3714130)
Document: ALA3714737
Inverse agonist activity at rat G-protein GSalpha fused GPR6 (unknown origin) expressed in HEK293 cell membranes assessed as cAMP accumulation pre-incubated for 30 mins by microbeta plate reader based assay1: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA3721176
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 271.39 | 0.95 | 0.95 |
| 269.38 | 2.31 | 2.31 |
| 265.36 | 0.89 | 0.89 |
| 263.35 | 2.25 | 2.25 |
| 333.36 | 1.91 | 1.91 |
| 331.34 | 3.27 | 3.27 |
| 321.47 | 2.19 | 2.19 |
| 319.46 | 3.55 | 3.55 |
| 299.81 | 1.54 | 1.54 |
| 297.79 | 2.90 | 2.90 |
| 295.39 | 0.90 | 0.90 |
| 293.37 | 2.26 | 2.26 |
| 295.39 | 0.90 | 0.90 |
| 293.37 | 2.26 | 2.26 |
| 279.39 | 1.20 | 1.20 |
| 277.37 | 2.56 | 2.56 |
| 301.34 | 1.17 | 1.17 |
| 299.33 | 2.53 | 2.53 |
| 283.35 | 1.03 | 1.03 |
| 281.34 | 2.39 | 2.39 |
| 283.35 | 1.03 | 1.03 |
| 281.34 | 2.39 | 2.39 |
| 283.35 | 1.03 | 1.03 |
| 281.34 | 2.39 | 2.39 |
| 315.42 | 2.04 | 2.04 |
| 313.41 | 3.40 | 3.40 |
| 315.42 | 2.04 | 2.04 |
| 313.41 | 3.40 | 3.40 |
| 321.45 | 2.11 | 2.11 |
| 319.44 | 3.46 | 3.46 |
| 255.32 | 0.48 | 0.48 |
| 253.31 | 1.84 | 1.84 |
| 282.35 | 1.85 | 1.85 |
| 256.31 | -0.12 | -0.12 |
| 254.30 | 1.24 | 1.24 |
| 433.87 | 2.75 | 2.75 |
| 431.85 | 4.11 | 4.11 |
| 344.42 | 3.21 | 3.21 |
| 312.45 | 1.01 | 1.01 |
| 266.35 | 0.29 | 0.29 |
| 264.33 | 1.64 | 1.64 |