Basic Information
ID: ALA3721192
Type: Functional
Description: Antagonist activity against CCR9 in human MOLT4 cells assessed as inhibition of human recombinant TECK-induced calcium response pre-treated before TECK stimulation by Flou-4-AM dye based FLIPR assay
Organism: Homo sapiens
Cell type: MOLT-4
Activity Charts
Bioactivity
Activity Types for Assay ALA3721192
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 444.94 | 4.30 | 4.30 |
| 454.90 | 4.13 | 4.13 |
| 454.90 | 4.13 | 4.13 |
| 428.90 | 4.28 | 4.28 |
| 543.67 | 3.43 | 3.43 |
| 455.95 | 4.89 | 4.89 |
| 439.88 | 4.42 | 4.42 |
| 538.98 | 4.45 | 4.45 |
| 498.99 | 3.44 | 3.44 |
| 571.10 | 4.39 | 4.39 |
| 454.90 | 2.96 | 2.96 |
| 468.92 | 4.43 | 4.43 |
| 482.01 | 5.56 | 5.56 |
| 506.01 | 3.00 | 3.00 |
| 467.93 | 5.04 | 5.04 |
| 467.91 | 4.97 | 4.97 |
| 450.91 | 4.22 | 4.22 |
| 456.96 | 3.18 | 3.18 |
| 538.03 | 6.02 | 6.02 |
| 588.09 | 7.17 | 7.17 |
| 487.97 | 5.92 | 5.92 |
| 437.91 | 4.76 | 4.76 |
| 499.03 | 5.24 | 5.24 |
| 408.91 | 3.78 | 3.78 |
| 426.88 | 2.44 | 2.44 |
| 409.90 | 2.19 | 2.19 |
| 400.89 | 4.33 | 4.33 |
| 412.49 | 4.55 | 4.55 |
| 428.94 | 5.06 | 5.06 |
| 463.39 | 5.72 | 5.72 |
| 442.97 | 5.37 | 5.37 |
| 456.83 | 4.67 | 4.67 |
| 402.86 | 3.78 | 3.78 |
| 475.36 | 4.66 | 4.66 |
| 442.97 | 5.37 | 5.37 |
| 453.95 | 4.94 | 4.94 |
| 458.97 | 4.61 | 4.61 |
| 442.97 | 5.37 | 5.37 |
| 479.39 | 4.96 | 4.96 |
| 458.97 | 4.61 | 4.61 |
| 428.94 | 5.06 | 5.06 |
| 430.91 | 4.55 | 4.55 |
| 439.88 | 4.42 | 4.42 |
| 473.39 | 5.17 | 5.17 |
| 444.94 | 4.30 | 4.30 |
| 475.04 | 5.79 | 5.79 |
| 430.48 | 4.69 | 4.69 |
| 460.94 | 4.10 | 4.10 |
| 458.92 | 3.87 | 3.87 |
| 458.97 | 4.61 | 4.61 |
| 430.48 | 4.69 | 4.69 |
| 442.97 | 5.37 | 5.37 |
| 453.91 | 4.73 | 4.73 |
| 444.94 | 4.86 | 4.86 |
| 488.95 | 3.42 | 3.42 |
| 463.39 | 5.72 | 5.72 |
| 429.93 | 4.46 | 4.46 |
| 444.94 | 4.86 | 4.86 |
| 430.91 | 4.55 | 4.55 |
| 470.86 | 4.97 | 4.97 |
| 464.95 | 3.48 | 3.48 |
| 458.92 | 3.87 | 3.87 |
| 501.37 | 3.06 | 3.06 |
| 448.93 | 5.43 | 5.43 |
| 444.94 | 4.04 | 4.04 |
| 444.94 | 4.86 | 4.86 |
| 428.94 | 5.06 | 5.06 |
| 442.97 | 5.45 | 5.45 |
| 428.94 | 5.06 | 5.06 |
| 507.03 | 4.47 | 4.47 |
| 456.83 | 4.67 | 4.67 |
| 480.95 | 2.72 | 2.72 |
| 386.86 | 4.08 | 4.08 |
| 464.95 | 3.48 | 3.48 |
| 495.38 | 3.28 | 3.28 |
| 429.93 | 4.46 | 4.46 |
| 501.28 | 4.77 | 4.77 |
| 460.94 | 3.28 | 3.28 |
| 486.98 | 4.61 | 4.61 |
| 439.88 | 4.42 | 4.42 |
| 460.94 | 4.10 | 4.10 |
| 451.73 | 4.53 | 4.53 |
| 475.04 | 5.79 | 5.79 |
| 458.97 | 5.07 | 5.07 |
| 472.95 | 4.18 | 4.18 |
| 486.86 | 4.21 | 4.21 |
| 460.94 | 4.10 | 4.10 |
| 507.03 | 4.47 | 4.47 |
| 440.87 | 3.82 | 3.82 |
| 455.88 | 3.66 | 3.66 |
| 458.97 | 5.07 | 5.07 |
| 444.94 | 4.30 | 4.30 |
| 467.93 | 5.04 | 5.04 |
| 427.91 | 3.41 | 3.41 |
| 445.34 | 4.44 | 4.44 |
| 472.95 | 4.18 | 4.18 |
| 429.93 | 4.46 | 4.46 |
| 428.94 | 5.06 | 5.06 |
| 486.86 | 4.21 | 4.21 |
| 439.88 | 4.42 | 4.42 |
| 405.86 | 3.11 | 3.11 |
| 514.05 | 4.90 | 4.90 |
| 428.90 | 4.28 | 4.28 |
| 471.97 | 3.79 | 3.79 |
| 414.87 | 3.97 | 3.97 |
| 440.87 | 3.82 | 3.82 |
| 527.67 | 4.20 | 4.20 |
| 467.93 | 5.04 | 5.04 |
| 454.90 | 4.13 | 4.13 |
| 440.83 | 4.79 | 4.79 |
| 485.99 | 4.13 | 4.13 |
| 450.93 | 3.17 | 3.17 |
| 447.31 | 3.88 | 3.88 |
| 453.91 | 4.73 | 4.73 |
| 453.91 | 4.73 | 4.73 |
| 497.96 | 4.32 | 4.32 |
| 489.96 | 4.05 | 4.05 |
| 501.00 | 4.38 | 4.38 |
| 485.01 | 5.14 | 5.14 |
| 481.96 | 5.08 | 5.08 |
| 485.01 | 5.14 | 5.14 |
| 491.93 | 2.98 | 2.98 |
| 516.02 | 3.93 | 3.93 |
| 518.01 | 4.83 | 4.83 |
| 519.98 | 3.76 | 3.76 |
| 495.99 | 5.39 | 5.39 |
| 487.97 | 3.15 | 3.15 |
| 475.93 | 3.74 | 3.74 |
| 477.95 | 4.30 | 4.30 |
| 503.98 | 4.52 | 4.52 |
| 486.98 | 4.07 | 4.07 |
| 501.00 | 4.38 | 4.38 |
| 485.01 | 5.14 | 5.14 |
| 459.47 | 3.23 | 3.23 |
| 481.96 | 5.08 | 5.08 |
| 470.98 | 4.83 | 4.83 |
| 470.98 | 4.83 | 4.83 |
| 467.93 | 4.54 | 4.54 |
| 485.01 | 5.14 | 5.14 |
| 481.96 | 5.08 | 5.08 |
| 417.92 | 4.39 | 4.39 |
| 497.96 | 4.32 | 4.32 |
| 430.48 | 4.69 | 4.69 |
| 511.99 | 4.63 | 4.63 |
| 473.94 | 2.84 | 2.84 |
| 495.99 | 5.39 | 5.39 |
| 485.99 | 4.38 | 4.38 |
| 500.02 | 4.69 | 4.69 |
| 486.98 | 4.46 | 4.46 |
| 481.96 | 5.08 | 5.08 |
| 457.94 | 3.60 | 3.60 |
| 501.99 | 3.62 | 3.62 |
| 474.01 | 4.32 | 4.32 |
| 453.91 | 4.73 | 4.73 |
| 486.98 | 4.07 | 4.07 |
| 470.98 | 4.83 | 4.83 |
| 473.94 | 2.84 | 2.84 |
| 467.93 | 5.04 | 5.04 |
| 501.99 | 3.62 | 3.62 |
| 485.99 | 4.38 | 4.38 |
| 438.89 | 5.03 | 5.03 |
| 459.37 | 5.00 | 5.00 |
| 438.89 | 5.03 | 5.03 |
| 457.94 | 3.60 | 3.60 |
| 458.92 | 3.99 | 3.99 |
| 454.89 | 4.27 | 4.27 |
| 516.41 | 5.73 | 5.73 |
| 444.90 | 3.52 | 3.52 |
| 470.86 | 4.97 | 4.97 |
| 498.73 | 4.37 | 4.37 |
| 495.99 | 5.39 | 5.39 |
| 434.97 | 5.13 | 5.13 |
| 497.96 | 4.32 | 4.32 |
| 495.99 | 5.39 | 5.39 |
| 432.93 | 3.80 | 3.80 |
| 446.98 | 5.27 | 5.27 |
| 481.96 | 5.08 | 5.08 |
| 432.93 | 3.80 | 3.80 |
| 483.50 | 4.71 | 4.71 |
| 512.03 | 5.01 | 5.01 |
| 481.96 | 5.08 | 5.08 |
| 427.91 | 3.98 | 3.98 |
| 439.88 | 4.42 | 4.42 |
| 441.94 | 4.37 | 4.37 |
| 455.97 | 4.76 | 4.76 |
| 474.92 | 3.22 | 3.22 |
| 454.96 | 5.50 | 5.50 |
| 456.94 | 4.29 | 4.29 |
| 467.93 | 5.04 | 5.04 |
| 430.91 | 4.08 | 4.08 |
| 416.89 | 4.40 | 4.40 |
| 444.94 | 4.12 | 4.12 |
| 407.28 | 4.42 | 4.42 |