ID: ALA3721193
Type: Functional
Description: Antagonist activity against CCR9 in human MOLT4 cells assessed as inhibition of human recombinant TECK-induced cell migration pre-treated for 15 mins before TECK stimulation for 150 mins by fluorescence based assay
Organism: Homo sapiens
Cell type: MOLT-4
Bioactivity
Activity Types for Assay ALA3721193
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
444.94 | 4.30 | 4.30 |
454.90 | 4.13 | 4.13 |
454.90 | 4.13 | 4.13 |
428.90 | 4.28 | 4.28 |
543.67 | 3.43 | 3.43 |
455.95 | 4.89 | 4.89 |
439.88 | 4.42 | 4.42 |
538.98 | 4.45 | 4.45 |
498.99 | 3.44 | 3.44 |
571.10 | 4.39 | 4.39 |
454.90 | 2.96 | 2.96 |
468.92 | 4.43 | 4.43 |
482.01 | 5.56 | 5.56 |
506.01 | 3.00 | 3.00 |
467.93 | 5.04 | 5.04 |
467.91 | 4.97 | 4.97 |
450.91 | 4.22 | 4.22 |
456.96 | 3.18 | 3.18 |
538.03 | 6.02 | 6.02 |
588.09 | 7.17 | 7.17 |
487.97 | 5.92 | 5.92 |
437.91 | 4.76 | 4.76 |
499.03 | 5.24 | 5.24 |
408.91 | 3.78 | 3.78 |
426.88 | 2.44 | 2.44 |
409.90 | 2.19 | 2.19 |
400.89 | 4.33 | 4.33 |
412.49 | 4.55 | 4.55 |
428.94 | 5.06 | 5.06 |
463.39 | 5.72 | 5.72 |
442.97 | 5.37 | 5.37 |
456.83 | 4.67 | 4.67 |
402.86 | 3.78 | 3.78 |
475.36 | 4.66 | 4.66 |
442.97 | 5.37 | 5.37 |
453.95 | 4.94 | 4.94 |
458.97 | 4.61 | 4.61 |
442.97 | 5.37 | 5.37 |
479.39 | 4.96 | 4.96 |
458.97 | 4.61 | 4.61 |
428.94 | 5.06 | 5.06 |
430.91 | 4.55 | 4.55 |
439.88 | 4.42 | 4.42 |
473.39 | 5.17 | 5.17 |
444.94 | 4.30 | 4.30 |
475.04 | 5.79 | 5.79 |
430.48 | 4.69 | 4.69 |
460.94 | 4.10 | 4.10 |
458.92 | 3.87 | 3.87 |
458.97 | 4.61 | 4.61 |
430.48 | 4.69 | 4.69 |
442.97 | 5.37 | 5.37 |
453.91 | 4.73 | 4.73 |
444.94 | 4.86 | 4.86 |
488.95 | 3.42 | 3.42 |
463.39 | 5.72 | 5.72 |
429.93 | 4.46 | 4.46 |
444.94 | 4.86 | 4.86 |
430.91 | 4.55 | 4.55 |
470.86 | 4.97 | 4.97 |
464.95 | 3.48 | 3.48 |
458.92 | 3.87 | 3.87 |
501.37 | 3.06 | 3.06 |
448.93 | 5.43 | 5.43 |
444.94 | 4.04 | 4.04 |
444.94 | 4.86 | 4.86 |
428.94 | 5.06 | 5.06 |
442.97 | 5.45 | 5.45 |
428.94 | 5.06 | 5.06 |
507.03 | 4.47 | 4.47 |
456.83 | 4.67 | 4.67 |
480.95 | 2.72 | 2.72 |
386.86 | 4.08 | 4.08 |
464.95 | 3.48 | 3.48 |
495.38 | 3.28 | 3.28 |
429.93 | 4.46 | 4.46 |
501.28 | 4.77 | 4.77 |
460.94 | 3.28 | 3.28 |
486.98 | 4.61 | 4.61 |
439.88 | 4.42 | 4.42 |
460.94 | 4.10 | 4.10 |
451.73 | 4.53 | 4.53 |
475.04 | 5.79 | 5.79 |
458.97 | 5.07 | 5.07 |
472.95 | 4.18 | 4.18 |
486.86 | 4.21 | 4.21 |
460.94 | 4.10 | 4.10 |
507.03 | 4.47 | 4.47 |
440.87 | 3.82 | 3.82 |
455.88 | 3.66 | 3.66 |
458.97 | 5.07 | 5.07 |
444.94 | 4.30 | 4.30 |
467.93 | 5.04 | 5.04 |
427.91 | 3.41 | 3.41 |
445.34 | 4.44 | 4.44 |
472.95 | 4.18 | 4.18 |
429.93 | 4.46 | 4.46 |
428.94 | 5.06 | 5.06 |
486.86 | 4.21 | 4.21 |
439.88 | 4.42 | 4.42 |
405.86 | 3.11 | 3.11 |
514.05 | 4.90 | 4.90 |
428.90 | 4.28 | 4.28 |
471.97 | 3.79 | 3.79 |
414.87 | 3.97 | 3.97 |
440.87 | 3.82 | 3.82 |
527.67 | 4.20 | 4.20 |
467.93 | 5.04 | 5.04 |
454.90 | 4.13 | 4.13 |
440.83 | 4.79 | 4.79 |
485.99 | 4.13 | 4.13 |
450.93 | 3.17 | 3.17 |
447.31 | 3.88 | 3.88 |
453.91 | 4.73 | 4.73 |
453.91 | 4.73 | 4.73 |
497.96 | 4.32 | 4.32 |
489.96 | 4.05 | 4.05 |
501.00 | 4.38 | 4.38 |
485.01 | 5.14 | 5.14 |
481.96 | 5.08 | 5.08 |
485.01 | 5.14 | 5.14 |
491.93 | 2.98 | 2.98 |
516.02 | 3.93 | 3.93 |
518.01 | 4.83 | 4.83 |
519.98 | 3.76 | 3.76 |
495.99 | 5.39 | 5.39 |
487.97 | 3.15 | 3.15 |
475.93 | 3.74 | 3.74 |
477.95 | 4.30 | 4.30 |
503.98 | 4.52 | 4.52 |
486.98 | 4.07 | 4.07 |
501.00 | 4.38 | 4.38 |
485.01 | 5.14 | 5.14 |
459.47 | 3.23 | 3.23 |
481.96 | 5.08 | 5.08 |
470.98 | 4.83 | 4.83 |
470.98 | 4.83 | 4.83 |
467.93 | 4.54 | 4.54 |
485.01 | 5.14 | 5.14 |
481.96 | 5.08 | 5.08 |
417.92 | 4.39 | 4.39 |
497.96 | 4.32 | 4.32 |
430.48 | 4.69 | 4.69 |
511.99 | 4.63 | 4.63 |
473.94 | 2.84 | 2.84 |
495.99 | 5.39 | 5.39 |
485.99 | 4.38 | 4.38 |
500.02 | 4.69 | 4.69 |
486.98 | 4.46 | 4.46 |
481.96 | 5.08 | 5.08 |
457.94 | 3.60 | 3.60 |
501.99 | 3.62 | 3.62 |
474.01 | 4.32 | 4.32 |
453.91 | 4.73 | 4.73 |
486.98 | 4.07 | 4.07 |
470.98 | 4.83 | 4.83 |
473.94 | 2.84 | 2.84 |
467.93 | 5.04 | 5.04 |
501.99 | 3.62 | 3.62 |
485.99 | 4.38 | 4.38 |
438.89 | 5.03 | 5.03 |
459.37 | 5.00 | 5.00 |
438.89 | 5.03 | 5.03 |
457.94 | 3.60 | 3.60 |
458.92 | 3.99 | 3.99 |
454.89 | 4.27 | 4.27 |
516.41 | 5.73 | 5.73 |
444.90 | 3.52 | 3.52 |
470.86 | 4.97 | 4.97 |
498.73 | 4.37 | 4.37 |
495.99 | 5.39 | 5.39 |
434.97 | 5.13 | 5.13 |
497.96 | 4.32 | 4.32 |
495.99 | 5.39 | 5.39 |
432.93 | 3.80 | 3.80 |
446.98 | 5.27 | 5.27 |
481.96 | 5.08 | 5.08 |
432.93 | 3.80 | 3.80 |
483.50 | 4.71 | 4.71 |
512.03 | 5.01 | 5.01 |
481.96 | 5.08 | 5.08 |
427.91 | 3.98 | 3.98 |
439.88 | 4.42 | 4.42 |
441.94 | 4.37 | 4.37 |
455.97 | 4.76 | 4.76 |
474.92 | 3.22 | 3.22 |
454.96 | 5.50 | 5.50 |
456.94 | 4.29 | 4.29 |
467.93 | 5.04 | 5.04 |
430.91 | 4.08 | 4.08 |
416.89 | 4.40 | 4.40 |
444.94 | 4.12 | 4.12 |
407.28 | 4.42 | 4.42 |