Basic Information
ID: ALA3721195
Type: Functional
Description: Antagonist activity against human P2X2/3 receptor expressed in CHOK1 cells assessed as inhibition of alpha,beta-meATP-induced calcium response incubated for 20 mins by Fluo-3AM dye based FLIPR assay
Organism: Homo sapiens
Cell type: CHO-K1
Activity Charts
Bioactivity
Activity Types for Assay ALA3721195
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 298.35 | 2.55 | 2.55 |
| 374.44 | 3.97 | 3.97 |
| 312.37 | 2.94 | 2.94 |
| 286.31 | 2.68 | 2.68 |
| 342.40 | 2.56 | 2.56 |
| 375.43 | 3.36 | 3.36 |
| 375.43 | 3.36 | 3.36 |
| 342.40 | 2.30 | 2.30 |
| 351.41 | 3.22 | 3.22 |
| 340.43 | 3.72 | 3.72 |
| 375.43 | 3.36 | 3.36 |
| 380.47 | 4.03 | 4.03 |
| 378.44 | 2.70 | 2.70 |
| 356.43 | 2.69 | 2.69 |
| 300.34 | 3.07 | 3.07 |
| 341.42 | 2.14 | 2.14 |
| 328.37 | 1.91 | 1.91 |
| 370.53 | ||
| 338.41 | 3.33 | 3.33 |
| 284.32 | 2.24 | 2.24 |
| 268.32 | 2.54 | 2.54 |
| 392.43 | 4.26 | 4.26 |
| 296.37 | 2.35 | 2.35 |
| 284.32 | 1.99 | 1.99 |
| 280.29 | 1.40 | 1.40 |
| 250.26 | 1.40 | 1.40 |
| 352.13 | 2.02 | 2.02 |
| 382.16 | 2.03 | 2.03 |
| 400.22 | 3.17 | 3.17 |
| 328.37 | 1.91 | 1.91 |
| 298.35 | 2.55 | 2.55 |
| 342.40 | 2.37 | 2.37 |
| 409.53 | 3.86 | 3.86 |
| 369.47 | 2.94 | 2.94 |
| 356.43 | 2.76 | 2.76 |
| 411.51 | 2.71 | 2.71 |
| 356.43 | 2.76 | 2.76 |
| 459.57 | 2.80 | 2.80 |
| 382.46 | 3.56 | 3.56 |
| 372.43 | 1.73 | 1.73 |
| 302.76 | 3.19 | 3.19 |
| 356.43 | 2.76 | 2.76 |