Basic Information
ID: ALA3721208
Type: Functional
Description: Antagonist activity against rat P2X3 receptor expressed in CHOK1 cells assessed as inhibition of alpha,beta-meATP-induced calcium response incubated for 20 mins by Fluo-3AM dye based FLIPR assay
Organism: Rattus norvegicus
Cell type: CHO-K1
Activity Charts
Bioactivity
Activity Types for Assay ALA3721208
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 516.66 | 3.62 | 3.62 |
| 462.62 | 4.07 | 4.07 |
| 366.49 | 4.55 | 4.55 |
| 350.42 | 4.08 | 4.08 |
| 350.42 | 4.08 | 4.08 |
| 366.49 | 4.55 | 4.55 |
| 366.49 | 4.55 | 4.55 |
| 498.67 | 3.48 | 3.48 |
| 498.67 | 3.48 | 3.48 |
| 366.49 | 4.55 | 4.55 |
| 516.66 | 3.62 | 3.62 |
| 439.56 | 4.38 | 4.38 |
| 421.57 | 4.24 | 4.24 |
| 421.57 | 4.24 | 4.24 |
| 459.97 | 4.72 | 4.72 |
| 537.08 | 3.97 | 3.97 |
| 537.08 | 3.97 | 3.97 |
| 459.97 | 4.72 | 4.72 |
| 416.55 | 5.70 | 5.70 |
| 400.51 | 5.07 | 5.07 |
| 418.50 | 5.21 | 5.21 |
| 480.61 | 4.21 | 4.21 |
| 380.51 | 4.86 | 4.86 |
| 379.53 | 4.47 | 4.47 |
| 350.49 | 5.31 | 5.31 |
| 428.56 | 6.29 | 6.29 |
| 412.56 | 6.45 | 6.45 |
| 364.51 | 5.70 | 5.70 |
| 370.45 | 4.04 | 4.04 |
| 414.53 | 5.37 | 5.37 |
| 476.65 | 4.38 | 4.38 |
| 438.55 | 4.73 | 4.73 |
| 423.54 | 3.91 | 3.91 |
| 437.57 | 4.25 | 4.25 |
| 451.59 | 4.69 | 4.69 |
| 400.51 | 5.07 | 5.07 |
| 388.44 | 4.52 | 4.52 |
| 350.42 | 4.08 | 4.08 |
| 364.45 | 4.39 | 4.39 |
| 435.59 | 4.54 | 4.54 |
| 483.66 | 3.94 | 3.94 |
| 380.51 | 4.86 | 4.86 |
| 462.62 | 4.07 | 4.07 |
| 366.49 | 4.20 | 4.20 |
| 366.49 | 4.20 | 4.20 |
| 380.51 | 4.86 | 4.86 |
| 352.46 | 3.90 | 3.90 |
| 382.49 | 3.52 | 3.52 |
| 388.49 | 5.87 | 5.87 |
| 427.51 | 4.69 | 4.69 |
| 428.56 | 5.38 | 5.38 |
| 443.58 | 5.33 | 5.33 |
| 395.53 | 4.41 | 4.41 |
| 404.89 | 5.03 | 5.03 |
| 350.42 | 4.08 | 4.08 |
| 443.58 | 5.33 | 5.33 |