Basic Information
ID: ALA3721244
Type: Functional
Description: Agonist activity at human GPR81 expressed in CHO-K1 cell membranes pre-incubated for 5 to 10 mins before [35S]GTPgammaS addition followed by further incubation for 60 mins by microbeta counting based [35S]GTPgammaS binding assay
Organism: Homo sapiens
Cell type: CHO-K1
Activity Charts
Bioactivity
Activity Types for Assay ALA3721244
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 211.22 | 2.13 | 2.13 |
| 245.67 | 2.78 | 2.78 |
| 255.23 | 1.85 | 1.85 |
| 301.35 | 3.72 | 3.72 |
| 251.29 | 2.61 | 2.61 |
| 225.25 | 2.43 | 2.43 |
| 253.31 | 3.08 | 3.08 |
| 287.32 | 3.79 | 3.79 |
| 226.24 | 1.71 | 1.71 |
| 229.21 | 2.27 | 2.27 |
| 241.25 | 2.13 | 2.13 |
| 225.25 | 2.43 | 2.43 |
| 254.29 | 2.27 | 2.27 |
| 240.27 | 2.02 | 2.02 |
| 253.31 | 3.00 | 3.00 |
| 239.28 | 2.74 | 2.74 |
| 257.32 | 2.85 | 2.85 |
| 225.25 | 2.43 | 2.43 |
| 239.28 | 2.74 | 2.74 |
| 239.28 | 2.74 | 2.74 |
| 239.28 | 2.74 | 2.74 |
| 304.15 | 3.20 | 3.20 |
| 305.13 | 2.47 | 2.47 |
| 217.25 | 2.19 | 2.19 |
| 240.27 | 2.02 | 2.02 |
| 245.67 | 2.78 | 2.78 |
| 245.67 | 2.78 | 2.78 |
| 241.25 | 2.13 | 2.13 |
| 243.24 | 2.57 | 2.57 |
| 279.22 | 3.14 | 3.14 |
| 229.21 | 2.27 | 2.27 |
| 189.22 | 1.86 | 1.86 |
| 239.28 | 2.74 | 2.74 |
| 239.28 | 2.74 | 2.74 |
| 253.31 | 3.25 | 3.25 |
| 239.28 | 2.69 | 2.69 |
| 304.15 | 3.20 | 3.20 |
| 294.24 | 2.73 | 2.73 |
| 293.25 | 3.45 | 3.45 |
| 287.32 | 3.79 | 3.79 |
| 246.66 | 2.17 | 2.17 |
| 256.22 | 2.03 | 2.03 |
| 290.12 | 2.89 | 2.89 |
| 280.11 | 3.43 | 3.43 |
| 338.59 | 3.85 | 3.85 |
| 259.70 | 3.09 | 3.09 |
| 203.25 | 2.25 | 2.25 |
| 231.30 | 3.03 | 3.03 |
| 280.11 | 3.43 | 3.43 |
| 263.66 | 2.92 | 2.92 |
| 297.21 | 3.28 | 3.28 |
| 280.11 | 3.43 | 3.43 |
| 297.21 | 3.28 | 3.28 |
| 314.56 | 4.09 | 4.09 |
| 347.22 | 4.16 | 4.16 |
| 313.67 | 3.80 | 3.80 |
| 358.12 | 3.91 | 3.91 |
| 244.23 | 1.85 | 1.85 |
| 247.20 | 2.40 | 2.40 |
| 243.24 | 2.57 | 2.57 |
| 259.70 | 3.09 | 3.09 |
| 263.66 | 2.92 | 2.92 |
| 262.22 | 1.99 | 1.99 |
| 258.26 | 2.16 | 2.16 |
| 274.71 | 2.67 | 2.67 |
| 278.67 | 2.50 | 2.50 |
| 258.26 | 2.16 | 2.16 |
| 219.24 | 1.49 | 1.49 |
| 280.11 | 3.43 | 3.43 |
| 245.28 | 2.21 | 2.21 |
| 247.30 | 2.00 | 2.00 |
| 329.57 | 3.67 | 3.67 |
| 328.59 | 4.39 | 4.39 |
| 314.56 | 4.09 | 4.09 |
| 309.76 | 4.24 | 4.24 |
| 295.73 | 3.93 | 3.93 |
| 253.31 | 3.05 | 3.05 |
| 239.28 | 2.74 | 2.74 |
| 318.17 | 3.51 | 3.51 |
| 304.15 | 3.20 | 3.20 |
| 275.31 | 3.59 | 3.59 |
| 328.59 | 4.39 | 4.39 |
| 329.57 | 3.67 | 3.67 |
| 275.31 | 3.59 | 3.59 |
| 261.28 | 3.28 | 3.28 |
| 276.30 | 2.86 | 2.86 |
| 310.74 | 3.51 | 3.51 |
| 290.33 | 3.17 | 3.17 |
| 289.34 | 3.90 | 3.90 |
| 233.27 | 1.61 | 1.61 |
| 231.25 | 1.82 | 1.82 |
| 217.27 | 2.64 | 2.64 |
| 246.31 | 2.61 | 2.61 |
| 245.33 | 3.42 | 3.42 |
| 245.33 | 3.34 | 3.34 |
| 233.27 | 1.61 | 1.61 |
| 235.31 | 2.21 | 2.21 |
| 229.28 | 2.50 | 2.50 |
| 251.29 | 2.61 | 2.61 |
| 266.30 | 2.20 | 2.20 |
| 358.12 | 3.91 | 3.91 |
| 263.66 | 2.92 | 2.92 |
| 308.11 | 3.03 | 3.03 |
| 332.40 | 3.10 | 3.10 |
| 324.57 | 3.54 | 3.54 |
| 251.29 | 3.00 | 3.00 |
| 295.22 | 3.02 | 3.02 |
| 309.25 | 3.33 | 3.33 |
| 310.24 | 2.61 | 2.61 |
| 271.35 | 3.16 | 3.16 |
| 297.21 | 3.28 | 3.28 |
| 259.70 | 3.09 | 3.09 |
| 260.68 | 2.36 | 2.36 |
| 269.35 | 3.06 | 3.06 |
| 283.38 | 3.37 | 3.37 |
| 284.36 | 2.64 | 2.64 |
| 243.24 | 2.57 | 2.57 |
| 267.28 | 3.28 | 3.28 |
| 231.30 | 2.89 | 2.89 |
| 285.73 | 3.66 | 3.66 |
| 311.29 | 3.74 | 3.74 |
| 325.32 | 4.05 | 4.05 |
| 326.30 | 3.32 | 3.32 |
| 335.29 | 3.90 | 3.90 |
| 329.67 | 3.68 | 3.68 |
| 231.30 | 2.95 | 2.95 |
| 251.72 | 3.30 | 3.30 |
| 304.15 | 3.20 | 3.20 |
| 324.57 | 3.54 | 3.54 |
| 369.02 | 3.65 | 3.65 |
| 313.67 | 3.80 | 3.80 |
| 265.74 | 3.54 | 3.54 |
| 259.35 | 3.51 | 3.51 |
| 345.73 | 4.39 | 4.39 |
| 285.73 | 3.66 | 3.66 |
| 259.70 | 3.09 | 3.09 |
| 304.15 | 3.20 | 3.20 |
| 263.73 | 3.15 | 3.15 |
| 231.30 | 2.82 | 2.82 |
| 245.33 | 3.12 | 3.12 |
| 311.36 | 1.98 | 1.98 |
| 384.21 | 2.23 | 2.23 |