Basic Information
ID: ALA3721246
Type: Binding
Description: Inhibition of human PFKFB3 expressed in Escherichia coli BL21 (DE3) assessed as reduction in NADH consumption using fructose-6-phosphate incubated for 15 mins by spectrophotometry based pyruvate kinase and LDH enzyme coupled kinetic assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3721246
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 276.30 | 3.23 | 3.23 |
| 289.34 | 3.57 | 3.57 |
| 274.32 | 3.83 | 3.83 |
| 278.29 | 3.67 | 3.67 |
| 274.32 | 3.83 | 3.83 |
| 278.29 | 3.67 | 3.67 |