Basic Information
ID: ALA3734079
Type: Functional
Description: Inhibition of human Orai1/STIM1 expressed in HEK293 cells assessed as intracellular calcium level after 30 mins by FLIPR assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA3734079
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 410.75 | 5.61 | 5.61 |
| 390.34 | 5.27 | 5.27 |
| 390.34 | 5.27 | 5.27 |
| 427.21 | 6.13 | 6.13 |
| 409.22 | 5.99 | 5.99 |
| 427.21 | 6.13 | 6.13 |
| 404.80 | 5.34 | 5.34 |
| 392.76 | 5.47 | 5.47 |
| 350.41 | 5.44 | 5.44 |
| 368.38 | 5.30 | 5.30 |
| 388.80 | 5.64 | 5.64 |
| 372.35 | 5.13 | 5.13 |
| 406.79 | 5.78 | 5.78 |
| 409.31 | 4.80 | 4.80 |
| 408.33 | 5.41 | 5.41 |
| 408.33 | 5.41 | 5.41 |
| 313.40 | 4.57 | 4.57 |
| 349.38 | 4.85 | 4.85 |
| 391.32 | 4.66 | 4.66 |
| 368.38 | 4.72 | 4.72 |
| 388.80 | 5.06 | 5.06 |
| 389.79 | 4.46 | 4.46 |
| 385.83 | 4.63 | 4.63 |
| 392.31 | 4.63 | 4.63 |
| 370.28 | 3.75 | 3.75 |
| 391.32 | 5.24 | 5.24 |
| 369.29 | 4.36 | 4.36 |
| 408.76 | 5.15 | 5.15 |
| 350.32 | 4.25 | 4.25 |
| 368.31 | 4.39 | 4.39 |
| 386.30 | 4.53 | 4.53 |
| 386.30 | 4.53 | 4.53 |
| 368.31 | 4.39 | 4.39 |
| 386.30 | 4.53 | 4.53 |
| 369.30 | 3.79 | 3.79 |
| 364.35 | 4.56 | 4.56 |
| 386.30 | 4.53 | 4.53 |
| 364.35 | 4.74 | 4.74 |
| 382.34 | 4.87 | 4.87 |
| 400.33 | 5.01 | 5.01 |
| 386.30 | 4.53 | 4.53 |
| 369.30 | 3.79 | 3.79 |
| 351.31 | 3.65 | 3.65 |
| 422.28 | 5.20 | 5.20 |
| 440.27 | 5.33 | 5.33 |
| 368.31 | 4.48 | 4.48 |
| 386.30 | 4.62 | 4.62 |
| 368.31 | 4.48 | 4.48 |
| 386.30 | 4.62 | 4.62 |
| 398.33 | 4.49 | 4.49 |
| 369.30 | 3.88 | 3.88 |
| 381.30 | 5.18 | 5.18 |
| 421.35 | 4.67 | 4.67 |
| 342.35 | 3.75 | 3.75 |
| 381.21 | 5.04 | 5.04 |
| 398.31 | 5.92 | 5.92 |
| 398.31 | 5.92 | 5.92 |
| 380.32 | 5.78 | 5.78 |
| 358.36 | 5.47 | 5.47 |
| 340.37 | 5.33 | 5.33 |
| 416.30 | 6.06 | 6.06 |
| 399.29 | 5.32 | 5.32 |
| 466.30 | 6.94 | 6.94 |
| 448.31 | 6.80 | 6.80 |
| 365.33 | 3.83 | 3.83 |