Basic Information
ID: ALA3734110
Type: Binding
Description: Inhibition of B-raf V600E mutant (unknown origin) expressed in Sf9 cells using biotin-MEK1substrate incubated for 1 hr
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA3734110
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 380.38 | 2.62 | 2.62 |
| 482.39 | 4.29 | 4.29 |
| 362.39 | 2.48 | 2.48 |
| 366.35 | 2.23 | 2.23 |
| 380.38 | 2.62 | 2.62 |
| 394.40 | 3.01 | 3.01 |
| 394.40 | 2.86 | 2.86 |
| 408.43 | 3.40 | 3.40 |
| 406.41 | 3.15 | 3.15 |
| 420.44 | 3.54 | 3.54 |
| 420.32 | 2.77 | 2.77 |
| 434.35 | 3.16 | 3.16 |
| 381.36 | 1.69 | 1.69 |
| 407.40 | 2.22 | 2.22 |
| 423.40 | 1.46 | 1.46 |
| 415.38 | 2.66 | 2.66 |
| 432.38 | 3.41 | 3.41 |
| 432.38 | 3.41 | 3.41 |
| 450.37 | 3.55 | 3.55 |
| 456.47 | 4.39 | 4.39 |
| 456.47 | 4.22 | 4.22 |
| 480.40 | 3.87 | 3.87 |
| 480.40 | 3.87 | 3.87 |
| 470.50 | 4.57 | 4.57 |
| 464.40 | 4.15 | 4.15 |
| 414.39 | 3.27 | 3.27 |
| 402.33 | 2.63 | 2.63 |
| 397.39 | 2.52 | 2.52 |
| 432.38 | 3.41 | 3.41 |
| 432.38 | 3.41 | 3.41 |
| 432.38 | 3.41 | 3.41 |
| 414.39 | 3.27 | 3.27 |
| 363.37 | 1.55 | 1.55 |
| 389.41 | 2.08 | 2.08 |
| 376.41 | 2.73 | 2.73 |
| 376.41 | 2.87 | 2.87 |
| 374.40 | 2.62 | 2.62 |
| 405.41 | 1.32 | 1.32 |
| 414.39 | 3.27 | 3.27 |
| 402.45 | 3.40 | 3.40 |
| 388.42 | 3.01 | 3.01 |
| 394.40 | 2.93 | 2.93 |
| 410.40 | 2.63 | 2.63 |
| 494.43 | 4.16 | 4.16 |
| 392.41 | 2.49 | 2.49 |
| 512.42 | 4.30 | 4.30 |
| 432.38 | 3.41 | 3.41 |
| 392.39 | 2.76 | 2.76 |
| 450.37 | 3.55 | 3.55 |
| 450.37 | 3.55 | 3.55 |
| 445.41 | 2.67 | 2.67 |