Basic Information
ID: ALA3734140
Type: Functional
Description: Antagonist activity against human P2X2/3 receptor expressed in HEK293/1321N1 cells assessed as inhibition of alpha,beta-meATP/ATP-induced calcium influx at 3 uM by Fluo-4 dye based FLIPR assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3734140
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 337.81 | 3.83 | 3.83 |
| 469.88 | 4.12 | 4.12 |
| 420.95 | 4.56 | 4.56 |
| 365.87 | 4.01 | 4.01 |
| 361.45 | 3.36 | 3.36 |
| 365.87 | 4.01 | 4.01 |
| 379.90 | 4.05 | 4.05 |
| 375.48 | 3.41 | 3.41 |
| 345.45 | 3.38 | 3.38 |
| 375.43 | 3.08 | 3.08 |
| 399.42 | 4.37 | 4.37 |
| 399.42 | 4.37 | 4.37 |
| 415.42 | 4.25 | 4.25 |
| 415.42 | 4.25 | 4.25 |
| 387.53 | 4.65 | 4.65 |
| 345.45 | 3.40 | 3.40 |
| 375.48 | 3.41 | 3.41 |
| 405.50 | 3.41 | 3.41 |
| 379.90 | 4.05 | 4.05 |
| 359.48 | 3.71 | 3.71 |
| 399.42 | 4.37 | 4.37 |
| 405.50 | 3.41 | 3.41 |
| 397.43 | 3.96 | 3.96 |
| 361.45 | 3.36 | 3.36 |
| 414.34 | 4.70 | 4.70 |
| 365.87 | 4.01 | 4.01 |
| 345.45 | 3.66 | 3.66 |
| 349.41 | 3.49 | 3.49 |
| 373.50 | 4.48 | 4.48 |
| 405.50 | 3.40 | 3.40 |
| 413.45 | 4.42 | 4.42 |
| 379.90 | 4.03 | 4.03 |
| 375.48 | 3.39 | 3.39 |
| 375.48 | 3.39 | 3.39 |
| 373.50 | 3.94 | 3.94 |
| 379.90 | 4.03 | 4.03 |
| 363.44 | 3.52 | 3.52 |
| 375.48 | 3.39 | 3.39 |
| 413.45 | 4.40 | 4.40 |
| 359.48 | 3.69 | 3.69 |
| 367.40 | 3.63 | 3.63 |
| 367.40 | 3.63 | 3.63 |
| 417.41 | 4.51 | 4.51 |
| 417.41 | 4.51 | 4.51 |
| 417.41 | 4.51 | 4.51 |
| 367.40 | 3.63 | 3.63 |
| 400.31 | 4.66 | 4.66 |
| 359.48 | 3.97 | 3.97 |
| 359.48 | 3.97 | 3.97 |
| 383.86 | 4.15 | 4.15 |
| 400.31 | 4.66 | 4.66 |
| 363.44 | 4.05 | 4.05 |
| 391.48 | 3.37 | 3.37 |
| 433.87 | 5.03 | 5.03 |
| 363.44 | 3.80 | 3.80 |
| 383.86 | 4.15 | 4.15 |
| 400.31 | 4.66 | 4.66 |
| 417.41 | 4.51 | 4.51 |
| 467.42 | 5.39 | 5.39 |