Basic Information
ID: ALA3734142
Type: Binding
Description: Inhibition of PFKFB3 (unknown origin) expressed in Escherichia coli assessed as fructose -2,6-bisphosphate level using fructose-6-phosphate as substrate and ATP measured after 10 mins by spectrophotometry
Format: BAO_0000019
Organism: Homo sapiens
Target: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(ALA2331053)
Document: ALA3727345
Inhibition of PFKFB3 (unknown origin) expressed in Escherichia coli assessed as fructose -2,6-bisphosphate level using fructose-6-phosphate as substrate and ATP measured after 10 mins by spectrophotometry: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA3734142
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 404.67 | 3.63 | 3.63 |
| 374.41 | 2.38 | 2.38 |
| 389.50 | 4.83 | 4.83 |
| 410.54 | 4.60 | 4.60 |
| 390.49 | 4.23 | 4.23 |
| 390.49 | 4.23 | 4.23 |
| 434.50 | 4.74 | 4.74 |
| 471.56 | 3.87 | 3.87 |
| 397.46 | 3.85 | 3.85 |
| 373.43 | 4.36 | 4.36 |
| 403.53 | 4.76 | 4.76 |
| 395.42 | 3.47 | 3.47 |
| 407.45 | 3.34 | 3.34 |
| 351.39 | 2.82 | 2.82 |
| 404.50 | 3.16 | 3.16 |
| 377.43 | 3.33 | 3.33 |
| 381.86 | 4.36 | 4.36 |
| 386.46 | 2.77 | 2.77 |
| 404.47 | 3.67 | 3.67 |
| 446.32 | 4.64 | 4.64 |
| 384.25 | 3.28 | 3.28 |
| 445.43 | 4.35 | 4.35 |
| 448.22 | 3.45 | 3.45 |
| 426.48 | 2.49 | 2.49 |
| 425.91 | 2.90 | 2.90 |
| 360.42 | 3.31 | 3.31 |
| 350.38 | 2.90 | 2.90 |
| 353.77 | 2.46 | 2.46 |
| 368.38 | 2.32 | 2.32 |