Basic Information
ID: ALA3734144
Type: Binding
Description: Inhibition of PFKFB4 (unknown origin) expressed in Escherichia coli assessed as ADP level preincubated for 15 mins followed by addition of fructose-6-phosphate as substrate and ATP measured after 40 mins by luciferase assay
Format: BAO_0000019
Organism: Homo sapiens
Target: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4(ALA3721311)
Document: ALA3727345
Inhibition of PFKFB4 (unknown origin) expressed in Escherichia coli assessed as ADP level preincubated for 15 mins followed by addition of fructose-6-phosphate as substrate and ATP measured after 40 mins by luciferase assay: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA3734144
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 389.50 | 4.83 | 4.83 |
| 396.51 | 4.29 | 4.29 |
| 377.43 | 3.33 | 3.33 |
| 438.22 | 3.99 | 3.99 |
| 431.53 | 2.91 | 2.91 |
| 413.48 | 3.40 | 3.40 |
| 417.90 | 4.05 | 4.05 |
| 397.49 | 3.70 | 3.70 |
| 381.86 | 4.36 | 4.36 |
| 371.45 | 3.19 | 3.19 |
| 377.44 | 3.72 | 3.72 |
| 389.44 | 3.33 | 3.33 |
| 381.86 | 4.36 | 4.36 |
| 398.22 | 2.57 | 2.57 |
| 407.45 | 3.34 | 3.34 |
| 419.44 | 3.67 | 3.67 |
| 435.89 | 4.19 | 4.19 |
| 397.86 | 4.07 | 4.07 |